Phosphoamidase

From Wikipedia, the free encyclopedia

In enzymology, a phosphoamidase (EC 3.9.1.1) is an enzyme that catalyzes the chemical reaction

N-phosphocreatine + H₂O creatine + phosphate

Thus, the two substrates of this enzyme are N-phosphocreatine and H₂O, whereas its two products are creatine and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphorus-nitrogen bonds. The systematic name of this enzyme class is phosphamide hydrolase. This enzyme is also called creatine phosphatase.

[edit] References

• IUBMB entry for 3.9.1.1
• BRENDA references for 3.9.1.1 (Recommended.)
• PubMed references for 3.9.1.1
• PubMed Central references for 3.9.1.1
• Google Scholar references for 3.9.1.1
• Parvin R, Smith RA (1969). "Phosphoramidates. V. Probable identity of rat liver microsomal glucose 6-phosphatase, phosphoramidase, and phosphoramidate-hexose phosphotransferase". Biochemistry. 8: 1748–55. doi:10.1021/bi00832a058. PMID 4308726. 
• Singer MF and Fruton JS (1957). "Some properties of beef spleen phosphoamidase". J. Biol. Chem. 229: 111–119. 
• Sundarajan TA and Sarma PS (1959). "Substrate specificity of phosphoprotein phosphatase from spleen". Biochem. J. 71: 537–544. 

[edit] External links

The CAS registry number for this enzyme class is 9001-79-0.

• IUBMB entry for 3.9.1.1

• KEGG entry for 3.9.1.1

• BRENDA entry for 3.9.1.1

• NiceZyme view of 3.9.1.1

• EC2PDB: PDB structures for 3.9.1.1

• PRIAM entry for 3.9.1.1

• PUMA2 entry for 3.9.1.1

• IntEnz: Integrated Enzyme entry for 3.9.1.1

• MetaCyc entry for 3.9.1.1

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050187: phosphoamidase

• AMIGO entry for GO code 0050187: phosphoamidase