Phosphatidylinositol a-mannosyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a phosphatidylinositol alpha-mannosyltransferase (EC 2.4.1.57) is an enzyme that catalyzes the chemical reaction in which at least one alpha-D-mannose residues are transferred from GDP-mannose to positions 6, 2 and others in 1-phosphatidyl-myo-inositol.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-mannose:1-phosphatidyl-1D-myo-inositol alpha-D-mannosyltransferase. Other names in common use include GDP mannose-phosphatidyl-myo-inositol alpha-mannosyltransferase, GDPmannose:1-phosphatidyl-myo-inositol alpha-D-mannosyltransferase, guanosine diphosphomannose-phosphatidyl-inositol, alpha-mannosyltransferase, and phosphatidyl-myo-inositol alpha-mannosyltransferase.

[edit] References

• IUBMB entry for 2.4.1.57
• BRENDA references for 2.4.1.57 (Recommended.)
• PubMed references for 2.4.1.57
• PubMed Central references for 2.4.1.57
• Google Scholar references for 2.4.1.57
• Brennan P, Ballou CE (1968). "Phosphatidylmyoinositol monomannoside in Propionibacterium shermanii". Biochem. Biophys. Res. Commun. 30: 69–75. doi:10.1016/0006-291X(68)90714-6. PMID 4295288. 

[edit] External links

The CAS registry number for this enzyme class is 37277-65-9.

• IUBMB entry for 2.4.1.57

• KEGG entry for 2.4.1.57

• BRENDA entry for 2.4.1.57

• NiceZyme view of 2.4.1.57

• EC2PDB: PDB structures for 2.4.1.57

• PRIAM entry for 2.4.1.57

• PUMA2 entry for 2.4.1.57

• IntEnz: Integrated Enzyme entry for 2.4.1.57

• MetaCyc entry for 2.4.1.57

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0043750: phosphatidylinositol alpha-mannosyltransferase

• AMIGO entry for GO code 0043750: phosphatidylinositol alpha-mannosyltransferase