Phosphate-transporting ATPase

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In enzymology, a phosphate-transporting ATPase (EC 3.6.3.27) is an enzyme that catalyzes the chemical reaction

ATP + H₂O + phosphateout $\rightleftharpoons$ ADP + phosphate + phosphatein

The 3 substrates of this enzyme are ATP, H₂O, and phosphate, whereas its two products are ADP and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (phosphate-importing). This enzyme is also called ABC phosphate transporter. This enzyme participates in abc transporters - general.

[edit] References

IUBMB entry for 3.6.3.27
BRENDA references for 3.6.3.27 (Recommended.)
PubMed references for 3.6.3.27
PubMed Central references for 3.6.3.27
Google Scholar references for 3.6.3.27
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Kuan G, Dassa E, Saurin W, Hofnung M, Saier MH Jr (1995). "Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases". Res. Microbiol. 146: 271–8. PMID 7569321.
R, Content J (1996). "Identification of a second Mycobacterium tuberculosis gene cluster encoding proteins of an ABC phosphate transporter". FEBS. Lett. 394: 206–12. doi:10.1016/0014-5793(96)00953-2. PMID 8843165.
Saier MH Jr (1998). "Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya". Adv. Microb. Physiol. 40: 81–136. PMID 9889977.
Griffiths JK and Sansom CE. "The Transporter Factsbook, Academic Press, San Diego, 1998".