Image:Phosphoadenosine phosphosulfate.png
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3'-phosphoadenosine 5'-phosphosulfate (PAPS)is the universal sulfuryl (Sulfonate) donor compound. PAPS is synthesized in two concerted step from inorganic sulfate and ATP catalyzed by the bifunctional enzyme PAPS synthase (PAPSS)(EC 2.7.7.4). The sulfotransferase enzymes use PAPS to transfer the sulfuryl group on to a recipient compound to form the respective sulfate ester. Upon sulfonation the physicochemical properties of the recipient molecule is altered. For example petromyzonol is a compound that is produced by the organism petromyzon marinus (sea lamprey). Using PAPS, the enzyme petromyzonol sulfotransferase (EC 2.8.2.31)transfers the sulfonate group onto petromyzonol to form petromyzonol sulfate. It has been reported that petromyzonol sulfate can serve as a migratory pheromone during the reproductive cycle of the sea lamprey.
[edit] Beschreibung
| Description |
Chemical structure of 3'-phosphoadenosine-5'-phosphosulfate |
|---|---|
| Source |
own work (drawn with MDL ISIS/Draw®) |
| Date |
2007-2-7 |
| Author |
Dschanz |
| Permission (Reusing this image) |
public domain |
[edit] Licensing
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| Date/Time | Dimensions | User | Comment | |
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| current | 19:07, 7 February 2007 | 420×368 (19 KB) | Dschanz | ({{Information |Description=Chemical structure of 3'-phosphoadenosine-5'-phosphosulfate |Source=own work (drawn with MDL ISIS/Draw<sup>®</sup>) |Date=2007-2-7 |Author=Dschanz |Permission=public domain |other_versions=- }}) |
