Phloroglucinol reductase

From Wikipedia, the free encyclopedia

In enzymology, a phloroglucinol reductase (EC 1.3.1.57) is an enzyme that catalyzes the chemical reaction

dihydrophloroglucinol + NADP⁺ phloroglucinol + NADPH + H⁺

Thus, the two substrates of this enzyme are dihydrophloroglucinol and NADP⁺, whereas its 3 products are phloroglucinol, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is dihydrophloroglucinol:NADP+ oxidoreductase. This enzyme participates in benzoate degradation via coa ligation.

[edit] References

• IUBMB entry for 1.3.1.57
• BRENDA references for 1.3.1.57 (Recommended.)
• PubMed references for 1.3.1.57
• PubMed Central references for 1.3.1.57
• Google Scholar references for 1.3.1.57
• Haddock JD, Ferry JG (1989). "Purification and properties of phloroglucinol reductase from Eubacterium oxidoreducens G-41". J. Biol. Chem. 264: 4423–7. PMID 2925649. 

[edit] External links

• IUBMB entry for 1.3.1.57

• KEGG entry for 1.3.1.57

• BRENDA entry for 1.3.1.57

• NiceZyme view of 1.3.1.57

• EC2PDB: PDB structures for 1.3.1.57

• PRIAM entry for 1.3.1.57

• PUMA2 entry for 1.3.1.57

• IntEnz: Integrated Enzyme entry for 1.3.1.57

• MetaCyc entry for 1.3.1.57

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0018510: phloroglucinol reductase

• AMIGO entry for GO code 0018510: phloroglucinol reductase