Phloretin hydrolase

From Wikipedia, the free encyclopedia

In enzymology, a phloretin hydrolase (EC 3.7.1.4) is an enzyme that catalyzes the chemical reaction

phloretin + H₂O phloretate + phloroglucinol

Thus, the two substrates of this enzyme are phloretin and H₂O, whereas its two products are phloretate and phloroglucinol.

This enzyme belongs to the family of hydrolases, specifically those acting on carbon-carbon bonds in ketonic substances. The systematic name of this enzyme class is 2',4,4',6'-tetrahydroxydehydrochalcone 1,3,5-trihydroxybenzenehydrolase. This enzyme is also called lactase-phlorizin hydrolase.

[edit] References

• IUBMB entry for 3.7.1.4
• BRENDA references for 3.7.1.4 (Recommended.)
• PubMed references for 3.7.1.4
• PubMed Central references for 3.7.1.4
• Google Scholar references for 3.7.1.4
• Minamikawa T, Jayasankar NP, Bohm BA, Taylor IE, Towers GH (1970). "An inducible hydrolase from Aspergillus niger, acting on carbon-carbon bonds, for phlorrhizin and other C-acylated phenols". Biochem. J. 116: 889–97. PMID 5441377. 

[edit] External links

The CAS registry number for this enzyme class is 37289-38-6.

• IUBMB entry for 3.7.1.4

• KEGG entry for 3.7.1.4

• BRENDA entry for 3.7.1.4

• NiceZyme view of 3.7.1.4

• EC2PDB: PDB structures for 3.7.1.4

• PRIAM entry for 3.7.1.4

• PUMA2 entry for 3.7.1.4

• IntEnz: Integrated Enzyme entry for 3.7.1.4

• MetaCyc entry for 3.7.1.4

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050180: phloretin hydrolase

• AMIGO entry for GO code 0050180: phloretin hydrolase