PHF8

From Wikipedia, the free encyclopedia

PHD finger protein 8

Identifiers

PHF8; ZNF422; DKFZp686E0868; KIAA1111; MRXSSD

External IDs

OMIM: 300560 MGI: 2444341 HomoloGene: 49405

Gene ontology
Molecular Function:	• protein binding • zinc ion binding • metal ion binding
Biological Process:	• regulation of transcription, DNA-dependent

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_015107 (mRNA)
NP_055922 (protein)

NM_177201 (mRNA)
NP_796175 (protein)

Location

n/a

Chr X: 146.86 - 146.97 Mb

Pubmed search

[1]

[2]

PHD finger protein 8, also known as PHF8, is a human gene.^[1]

[edit] References

^ Entrez Gene: PHF8 PHD finger protein 8.

[edit] Further reading

Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99-106. PMID 12168954.
Siderius LE, Hamel BC, van Bokhoven H, et al. (2000). "X-linked mental retardation associated with cleft lip/palate maps to Xp11.3-q21.3.". Am. J. Med. Genet. 85 (3): 216-20. PMID 10398231.
Kikuno R, Nagase T, Ishikawa K, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 6 (3): 197-205. PMID 10470851.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130-5. doi:10.1073/pnas.0404720101. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome.". Nature 434 (7031): 325-37. doi:10.1038/nature03440. PMID 15772651.
Laumonnier F, Holbert S, Ronce N, et al. (2006). "Mutations in PHF8 are associated with X linked mental retardation and cleft lip/cleft palate.". J. Med. Genet. 42 (10): 780-6. doi:10.1136/jmg.2004.029439. PMID 16199551.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Koivisto AM, Ala-Mello S, Lemmelä S, et al. (2007). "Screening of mutations in the PHF8 gene and identification of a novel mutation in a Finnish family with XLMR and cleft lip/cleft palate.". Clin. Genet. 72 (2): 145-9. doi:10.1111/j.1399-0004.2007.00836.x. PMID 17661819.