PHF16

From Wikipedia, the free encyclopedia


PHD finger protein 16
Identifiers
Symbol(s) PHF16; KIAA0215; JADE3; MGC138748; MGC138749
External IDs OMIM: 300618 MGI: 2148019 HomoloGene: 40981
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 9767 382207
Ensembl ENSG00000102221 ENSMUSG00000037315
Uniprot Q92613 Q6IE82
Refseq NM_001077445 (mRNA)
NP_001070913 (protein)		 NM_199317 (mRNA)
NP_955021 (protein)
Location Chr X: 46.66 - 46.81 Mb Chr X: 19.58 - 19.68 Mb
Pubmed search [1] [2]

PHD finger protein 16, also known as PHF16, is a human gene.[1]

This gene is part of a gene cluster on chromosome Xp11.23. The encoded protein contains a zinc finger motif often found in transcriptional regulators, however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding the same protein.[1]

[edit] References

  1. ^ a b Entrez Gene: PHF16 PHD finger protein 16.

[edit] Further reading

  • Nagase T, Seki N, Ishikawa K, et al. (1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.". DNA Res. 3 (5): 321–9, 341–54. PMID 9039502. 
  • Szelei J, Soto AM, Geck P, et al. (2000). "Identification of human estrogen-inducible transcripts that potentially mediate the apoptotic response in breast cancer.". J. Steroid Biochem. Mol. Biol. 72 (3-4): 89–102. PMID 10775800. 
  • Thiselton DL, McDowall J, Brandau O, et al. (2002). "An integrated, functionally annotated gene map of the DXS8026-ELK1 interval on human Xp11.3-Xp11.23: potential hotspot for neurogenetic disorders.". Genomics 79 (4): 560–72. doi:10.1006/geno.2002.6733. PMID 11944989. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Tzouanacou E, Tweedie S, Wilson V (2003). "Identification of Jade1, a gene encoding a PHD zinc finger protein, in a gene trap mutagenesis screen for genes involved in anteroposterior axis development.". Mol. Cell. Biol. 23 (23): 8553–2. PMID 14612400. 
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome.". Nature 434 (7031): 325–37. doi:10.1038/nature03440. PMID 15772651. 
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560. 
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
 This article on a gene on the X chromosome and/or its associated protein is a stub. You can help Wikipedia by expanding it.