Talk:Phenylketonuria

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To-do list for Phenylketonuria: edit · history · watch · refresh

Strike through when completed:

  • Flesh out lead and article in general
  • Add section on types
  • Add section on current work (there's alot of quite advanced research going on into cures, do a google on "PKU Mice" for some interesting papers if you have time.)
  • Reference for statement "Phenylketonuria can also possibly exist in mice"
  • Find a more definative referance about PKU mice rather than a paper which simply uses them.
  • Move comments about babies with PKU drinking breastmilk out of Maternal PKU section and up into section about PKU. Verify comment/research about breastfeeding mothers of PKU babies eating low phe diet.
  • Add definition for commonly used term phe
  • Add more images - one of Ivar Følling, a person with the disorder, and a blood sample/culture to test for the condition.
  • Review 'references' - many should be moved to external links or removed entirely.
  • Redirect PKU to this page
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Contents

[edit] Folling's Disease

Known as Folling's Disease in Norway, not in the US or most other countries.

Please i would like to know the reference about 'compulsive licking of others and small children ears". i have searched the web for a corroborating medical article on that and found none. thank you.82.198.0.170 (talk) 10:37, 14 March 2008 (UTC)

Reference:

The Discovery of Phenylketonuria The Story of a Young Couple, Two Retarded Children, and a Scientist Pediatrics, Jan. 2000. Siegried A. Centerwall, Willard R. Centerwall

Life: The Science of Biology Purves. not sure of other info for book... This is a American High School AP Biology book, in it PKU is called phenylketnouria. Følling's Disase could easily convey the same disease though and may not confuse too much...--Randalllin 06:24, 22 December 2006 (UTC)

[edit] Can you have it?

Can you have this disorder and not know? Are people affected by it and seem normal? —The preceding unsigned comment was added by Energman (talk • contribs) 1st September 2006.

Quick answer: No, if you had pku and wern't treated from birth you would be severly mentally damaged from the toxic phe levels in your blood and Yes people affected (and treated from birth) are undetectable from anyone else, if someone you knew had pku you would never realise unless they chose to tell you 81.137.243.44 15:41, 27 October 2006 (UTC)

Hang on, I just thought about what you wrote, SEEM normal? We ARE normal thank you very much! 81.137.243.44 15:44, 27 October 2006 (UTC)

I have PKU and am only slightly affected by it and no you can't have PKU and not know it the doctor always tell parents a couple of weeks later. —The preceding unsigned comment was added by Cutie fo eva (talk • contribs) 11th September 2006.

only in developed countries is testing for PKU available.-Randalllin 05:12, 7 January 2007 (UTC)

Sometimes mild forms of PKU can be missed during NBS, although I understand technology is getting better and those chances are being lowered. I met a couple who had a baby girl with a mild PKU and they restested her older sisters and found one of them also had a mild PKU that had not been caught during NBS... it is mild enough that they won't need to worry about a diet until they decide to have children. If you had a severe mutation (or classic PKU) and were not diagnosed/treated you would have severe brain damage, but a mild case may not. The people I know with PKU are completely normal except for their diet.

[edit] No starchy foods?

This article says people with PKU are supposed to avoid starchy foods.... I have had PKU all my life and NEVER heard this. This article lists bread and pasta, which I eat sparingly, but I have always eaten all the corn and potatoes I want. Does anyone have an validation to this claim?

MistressOfSnape 05:54, 12 February 2007 (UTC)MistressOfSnape

Hi!

who is at risk for PKU and is it possible for you to get Pku later on in your life? it may have been a recessive gene from your mother or father...?


no.. you have PKU from birth.. it doesnt develop over time or anything like that. —Preceding unsigned comment added by 77.100.163.61 (talk) 21:50, 9 September 2007 (UTC)

An important thing to remember if you have pku is that party pills containing X factor are dangerous if you suffer from this disease —Preceding unsigned comment added by 85.69.70.130 (talk) 12:19, 6 November 2007 (UTC)

Since Phenylalanine is important in the role of dopamine production (phenylalanine -> tyrosine -> L-DOPA -> dopamine) should the article mention something about what foods might replace tyrosine in PKU patient's diets. Dopamine is incredibly important to brain function. 75.73.31.54 (talk) 15:23, 15 February 2008 (UTC)

[edit] Asbjørn Følling

Something strange is going on in the last sentence of the openning section. I don't know what was meant to be there, but I'm guessing there's a code error. My suggestion to fix this is to make a section for "discovery", but I'm not knowledgeable enough on PKU to do this. RitRat (talk) 18:03, 7 December 2007 (UTC)