Phenylacetyl-CoA hydrolase

From Wikipedia, the free encyclopedia

In enzymology, a phenylacetyl-CoA hydrolase (EC 3.1.2.25) is an enzyme that catalyzes the chemical reaction

phenylglyoxylyl-CoA + H₂O phenylglyoxylate + CoA

Thus, the two substrates of this enzyme are phenylglyoxylyl-CoA and H₂O, whereas its two products are phenylglyoxylate and CoA.

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is phenylglyoxylyl-CoA hydrolase.

[edit] References

• IUBMB entry for 3.1.2.25
• BRENDA references for 3.1.2.25 (Recommended.)
• PubMed references for 3.1.2.25
• PubMed Central references for 3.1.2.25
• Google Scholar references for 3.1.2.25
• Rhee SK, Fuchs G (1999). "Phenylacetyl-CoA:acceptor oxidoreductase, a membrane-bound molybdenum-iron-sulfur enzyme involved in anaerobic metabolism of phenylalanine in the denitrifying bacterium Thauera aromatica". Eur. J. Biochem. 262: 507–15. doi:10.1046/j.1432-1327.1999.00399.x. PMID 10336636. 
• Schneider S, Fuchs G (1998). "Phenylacetyl-CoA:acceptor oxidoreductase, a new alpha-oxidizing enzyme that produces phenylglyoxylate. Assay, membrane localization, and differential production in Thauera aromatica". Arch. Microbiol. 169: 509–16. doi:10.1007/s002030050604. PMID 9575237. 

[edit] External links

• IUBMB entry for 3.1.2.25

• KEGG entry for 3.1.2.25

• BRENDA entry for 3.1.2.25

• NiceZyme view of 3.1.2.25

• EC2PDB: PDB structures for 3.1.2.25

• PRIAM entry for 3.1.2.25

• PUMA2 entry for 3.1.2.25

• IntEnz: Integrated Enzyme entry for 3.1.2.25

• MetaCyc entry for 3.1.2.25

• Atomic-resolution structures of enzymes belonging to this class