Phenotypic switching
From Wikipedia, the free encyclopedia
Phenotypic switching (a.k.a. phenotypic dimorphism) is switching between two cell-types. An example is Candida albicans, which, when it infects host tissue, switches from the usual unicellular yeast-like form of into an invasive, multicellular filamentous form.[1] This switching between two cell-types is known as dimorphism.
Phenotypic switching in C.albicans include the switch from white cells to opaque cells in need for sexual mating.
[edit] References
- ^ Kumamoto CA, Vinces MD (2005). "Contributions of hyphae and hypha-co-regulated genes to Candida albicans virulence". Cell. Microbiol. 7 (11): 1546–54. doi:. PMID 16207242.
[edit] External links
- Endocrine Abstracts"Are Hox genes responsible for the phenotypic switching and zonation of the adult adrenal cortex?"
- American Society for Clinical Investigation "Phenotypic switching in the fungal pathogen Cryptococcus neoformans"
- American Society for Microbiology "Control of White-Opaque Phenotypic Switching in Candida albicans by the Efg1p Morphogenetic Regulator"
- Conference on Retroviruses and Opportunistic Infections "Repeated phenotypic switching of HIV-1 in AIDS patients sampled regularly over 2 years."
