PGM1

From Wikipedia, the free encyclopedia

Phosphoglucomutase 1

PDB rendering based on 1c47.

Available structures: 1c47, 1c4g, 1jdy, 1lxt, 1vkl, 3pmg

Identifiers

Symbol(s)

PGM1;

External IDs

OMIM: 171900 MGI: 97565 HomoloGene: 1979

Gene ontology
Molecular Function:	• magnesium ion binding • phosphoglucomutase activity • isomerase activity
Cellular Component:	• cytoplasm
Biological Process:	• carbohydrate metabolic process • glucose metabolic process • gluconeogenesis • glycolysis

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_002633 (mRNA)
NP_002624 (protein)

NM_028132 (mRNA)
NP_082408 (protein)

Location

Chr 1: 63.83 - 63.9 Mb

Chr 4: 99.43 - 99.49 Mb

Pubmed search

[1]

[2]

Phosphoglucomutase 1, also known as PGM1, is a human gene.^[1]

[edit] References

^ Entrez Gene: PGM1 phosphoglucomutase 1.

[edit] Further reading

Whitehouse DB, Putt W, Lovegrove JU, et al. (1992). "Phosphoglucomutase 1: complete human and rabbit mRNA sequences and direct mapping of this highly polymorphic marker on human chromosome 1.". Proc. Natl. Acad. Sci. U.S.A. 89 (1): 411-5. PMID 1530890.
Dawson SJ, White LA (1992). "Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin.". J. Infect. 24 (3): 317-20. PMID 1602151.
Herbich J, Szilvassy J, Schnedl W (1985). "Gene localisation of the PGM1 enzyme system and the Duffy blood groups on chromosome No. 1 by means of a new fragile site at 1p31.". Hum. Genet. 70 (2): 178-80. PMID 3159642.
Douglas GR, McAlpine PJ, Hamerton JL (1973). "Regional localization of loci for human PGM and 6PGD on human chromosome one by use of hybrids of Chinese hamster-human somatic cells.". Proc. Natl. Acad. Sci. U.S.A. 70 (10): 2737-40. PMID 4517931.
Takahashi N, Neel JV (1993). "Intragenic recombination at the human phosphoglucomutase 1 locus: predictions fulfilled.". Proc. Natl. Acad. Sci. U.S.A. 90 (22): 10725-9. PMID 7902567.
March RE, Putt W, Hollyoake M, et al. (1993). "The classical human phosphoglucomutase (PGM1) isozyme polymorphism is generated by intragenic recombination.". Proc. Natl. Acad. Sci. U.S.A. 90 (22): 10730-3. PMID 7902568.
Putt W, Ives JH, Hollyoake M, et al. (1994). "Phosphoglucomutase 1: a gene with two promoters and a duplicated first exon.". Biochem. J. 296 ( Pt 2): 417-22. PMID 8257433.
Edwards YH, Putt W, Fox M, Ives JH (1996). "A novel human phosphoglucomutase (PGM5) maps to the centromeric region of chromosome 9.". Genomics 30 (2): 350-3. doi:10.1006/geno.1995.9866. PMID 8586438.
Moiseeva EP, Belkin AM, Spurr NK, et al. (1996). "A novel dystrophin/utrophin-associated protein is an enzymatically inactive member of the phosphoglucomutase superfamily.". Eur. J. Biochem. 235 (1-2): 103-13. PMID 8631316.
Landar A, Caddell G, Chessher J, Zimmer DB (1997). "Identification of an S100A1/S100B target protein: phosphoglucomutase.". Cell Calcium 20 (3): 279-85. PMID 8894274.
Yip SP, Lovegrove JU, Rana NA, et al. (2000). "Mapping recombination hotspots in human phosphoglucomutase (PGM1).". Hum. Mol. Genet. 8 (9): 1699-706. PMID 10441333.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Sergeev AS, Agapova RK, Bogadel'nikova IV, Perel'man MI (2003). "[The use of discrete characters in discriminant analysis for diagnosis of pulmonary tuberculosis and for classification of patients differing in treatment efficiency based on polymorphisms at nine codominant loci-HP, GC, TF, PI, PGM1, GLO1, C3, ACP1 and ESD]". Genetika 39 (7): 996-1002. PMID 12942785.
Gururaj A, Barnes CJ, Vadlamudi RK, Kumar R (2004). "Regulation of phosphoglucomutase 1 phosphorylation and activity by a signaling kinase.". Oncogene 23 (49): 8118-27. doi:10.1038/sj.onc.1207969. PMID 15378030.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Takahashi K, Inuzuka M, Ingi T (2005). "Cellular signaling mediated by calphoglin-induced activation of IPP and PGM.". Biochem. Biophys. Res. Commun. 325 (1): 203-14. doi:10.1016/j.bbrc.2004.10.021. PMID 15522220.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315-21. doi:10.1038/nature04727. PMID 16710414.