PFTK1

From Wikipedia, the free encyclopedia

PFTAIRE protein kinase 1

Identifiers

PFTK1; KIAA0834; PFTAIRE1

External IDs

OMIM: 610679 MGI: 894318 HomoloGene: 7888

Gene ontology
Molecular Function:	• nucleotide binding • protein serine/threonine kinase activity • ATP binding • transferase activity
Cellular Component:	• nucleus • cytoplasm
Biological Process:	• protein amino acid phosphorylation

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_012395 (mRNA)
NP_036527 (protein)

NM_011074 (mRNA)
NP_035204 (protein)

Location

Chr 7: 90.06 - 90.68 Mb

Chr 5: 4.81 - 5.39 Mb

Pubmed search

[1]

[2]

PFTAIRE protein kinase 1, also known as PFTK1, is a human gene.^[1]

[edit] References

^ Entrez Gene: PFTK1 PFTAIRE protein kinase 1.

[edit] Further reading

Lazzaro MA, Albert PR, Julien JP (1997). "A novel cdc2-related protein kinase expressed in the nervous system.". J. Neurochem. 69 (1): 348–64. PMID 9202329.
Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 5 (6): 355–64. PMID 10048485.
Yang T, Chen JY (2001). "Identification and cellular localization of human PFTAIRE1.". Gene 267 (2): 165–72. PMID 11313143.
Yang T, Gao YK, Chen JY (2002). "KIAA0202, a human septin family member, interacting with hPFTAIRE1.". Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao 34 (4): 520–5. PMID 12098780.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767–72. doi:10.1126/science.1083423. PMID 12690205.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells.". Science 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153.
Gao Y, Jiang M, Yang T, et al. (2006). "A Cdc2-related protein kinase hPFTAIRE1 from human brain interacting with 14-3-3 proteins.". Cell Res. 16 (6): 539–47. doi:10.1038/sj.cr.7310071. PMID 16775625.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.
Shu F, Lv S, Qin Y, et al. (2007). "Functional characterization of human PFTK1 as a cyclin-dependent kinase.". Proc. Natl. Acad. Sci. U.S.A. 104 (22): 9248–53. doi:10.1073/pnas.0703327104. PMID 17517622.
Denoeud F, Kapranov P, Ucla C, et al. (2007). "Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions.". Genome Res. 17 (6): 746–59. doi:10.1101/gr.5660607. PMID 17567994.