PEX26

From Wikipedia, the free encyclopedia

Peroxisome biogenesis factor 26

Identifiers

PEX26; FLJ20695; PEX26M1T; Pex26pM1T

External IDs

OMIM: 608666 MGI: 1921293 HomoloGene: 9922

Gene ontology
Molecular Function:	• protein binding
Cellular Component:	• peroxisome • integral to peroxisomal membrane • membrane • integral to membrane
Biological Process:	• protein transport • protein import into peroxisome membrane

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_017929 (mRNA)
NP_060399 (protein)

NM_028730 (mRNA)
NP_083006 (protein)

Location

n/a

Chr 6: 121.15 - 121.16 Mb

Pubmed search

[1]

[2]

Peroxisome biogenesis factor 26, also known as PEX26, is a human gene.^[1]

[edit] References

^ Entrez Gene: PEX26 peroxisome biogenesis factor 26.

[edit] Further reading

Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22.". Nature 402 (6761): 489-95. doi:10.1038/990031. PMID 10591208.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Matsumoto N, Tamura S, Fujiki Y (2003). "The pathogenic peroxin Pex26p recruits the Pex1p-Pex6p AAA ATPase complexes to peroxisomes.". Nat. Cell Biol. 5 (5): 454-60. doi:10.1038/ncb982. PMID 12717447.
Matsumoto N, Tamura S, Furuki S, et al. (2003). "Mutations in novel peroxin gene PEX26 that cause peroxisome-biogenesis disorders of complementation group 8 provide a genotype-phenotype correlation.". Am. J. Hum. Genet. 73 (2): 233-46. PMID 12851857.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome.". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMID 15461802.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Fransen M, Vastiau I, Brees C, et al. (2005). "Analysis of human Pex19p's domain structure by pentapeptide scanning mutagenesis.". J. Mol. Biol. 346 (5): 1275-86. doi:10.1016/j.jmb.2005.01.013. PMID 15713480.
Weller S, Cajigas I, Morrell J, et al. (2005). "Alternative splicing suggests extended function of PEX26 in peroxisome biogenesis.". Am. J. Hum. Genet. 76 (6): 987-1007. doi:10.1086/430637. PMID 15858711.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
Furuki S, Tamura S, Matsumoto N, et al. (2006). "Mutations in the peroxin Pex26p responsible for peroxisome biogenesis disorders of complementation group 8 impair its stability, peroxisomal localization, and interaction with the Pex1p x Pex6p complex.". J. Biol. Chem. 281 (3): 1317-23. doi:10.1074/jbc.M510044200. PMID 16257970.
Halbach A, Landgraf C, Lorenzen S, et al. (2006). "Targeting of the tail-anchored peroxisomal membrane proteins PEX26 and PEX15 occurs through C-terminal PEX19-binding sites.". J. Cell. Sci. 119 (Pt 12): 2508-17. doi:10.1242/jcs.02979. PMID 16763195.
Tamura S, Yasutake S, Matsumoto N, Fujiki Y (2006). "Dynamic and functional assembly of the AAA peroxins, Pex1p and Pex6p, and their membrane receptor Pex26p.". J. Biol. Chem. 281 (38): 27693-704. doi:10.1074/jbc.M605159200. PMID 16854980.