Perenelle Flamel
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Perenelle Flamel (b.1340) was the wife of the famous 15th century alchemist Nicholas Flamel. Perenelle was a widow and married Nicolas Flamel at the age of 40. Together they had no children but used their enormous wealth to care for the sick and poor.
Nicholas Flamel was an alchemist whose central quest was the search for the philosopher's stone, and the elixir of life that would supposedly achieve immortality. However, Perenelle was actually a serious alchemist in her own right, and worked with her husband on the alchemical quest as his partner. It was Perenelle's nephew to whom Nicholas Flamel passed down the knowledge that he had gained from the book of Abraham the Jew. Perenelle is reported to have died before Nicolas, but the legends maintain that both of them still live to this day, through the use of the philosopher's stone. She was also believed to be a sorceress of sorts, as shown in her love for the magical arts.
[edit] Perenelle in Fiction
Nicolas and Perenelle Flamel feature in the novels Harry Potter and the Philosopher's Stone by British author J.K. Rowling, and The Alchemyst:the Secrets of the Immortal Nicholas Flamel by Irish author Michael Scott.