PERP

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PERP, TP53 apoptosis effector
Identifiers
Symbol(s) PERP; KCP1; KRTCAP1; PIGPC1; RP3-496H19.1; THW; dJ496H19.1
External IDs OMIM: 609301 MGI: 1929938 HomoloGene: 11098
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 64065 64058
Ensembl ENSG00000112378 ENSMUSG00000019851
Uniprot Q96FX8 Q9JK95
Refseq NM_022121 (mRNA)
NP_071404 (protein)		 NM_022032 (mRNA)
NP_071315 (protein)
Location Chr 6: 138.45 - 138.47 Mb Chr 10: 18.53 - 18.55 Mb
Pubmed search [1] [2]

PERP, TP53 apoptosis effector, also known as PERP, is a human gene.[1]


PERP is a direct transcriptional target of p53.

[edit] References

  1. ^ Entrez Gene: PERP PERP, TP53 apoptosis effector.

[edit] Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149. 
  • Attardi LD, Reczek EE, Cosmas C, et al. (2000). "PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family.". Genes Dev. 14 (6): 704-18. PMID 10733530. 
  • Hildebrandt T, Preiherr J, Tarbé N, et al. (2000). "Identification of THW, a putative new tumor suppressor gene.". Anticancer Res. 20 (5A): 2801-9. PMID 11062687. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Bonkobara M, Das A, Takao J, et al. (2003). "Identification of novel genes for secreted and membrane-anchored proteins in human keratinocytes.". Br. J. Dermatol. 148 (4): 654-64. PMID 12752121. 
  • Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805-11. doi:10.1038/nature02055. PMID 14574404. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Ihrie RA, Attardi LD (2004). "Perp-etrating p53-dependent apoptosis.". Cell Cycle 3 (3): 267-9. PMID 14726658. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117-26. doi:10.1093/dnares/12.2.117. PMID 16303743. 
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