Talk:Pentosidine

From Wikipedia, the free encyclopedia

Molecular and Cellular Biology WikiProject
MCB Portal
This article is within the scope of the Molecular and Cellular Biology WikiProject. To participate, visit the WikiProject for more information. The WikiProject's current monthly collaboration is focused on improving Restriction enzyme.
Stub This article has been rated as Stub-Class on the assessment scale.
Low This article is on a subject of Low-importance within molecular and cellular biology.

Article Grading: The following comments were left by the quality and importance raters: (edit · history · refresh · how to use this template)

Good so far:

  • Several reasonable references, well formatted
  • Chembox

Still need:

  • First characterization, proof of structure
  • Diagram in chembox
  • Photo of pentosidine in cells (saw several at Google images).
  • Diagram of the formation of pentosidine from sugars, proteins, ROS.
  • Much more text about pentosidine as a marker for AGE, especially in diabetes.
    • Is it a factor in other plaque disease, like Alzheimers and atherosclerosis?
    • Pentosidine is a marker for elevated glucose, as is A1c. But they pentosidine is more sensitive to oxidation. Discuss relation to ROS
  • Detail on how pentosidine is assayed.
    • Since its a fluorescent compound, a spectrum would be nice.
  • How pentosidine (and other AGE) are cleared from the body.

David.Throop (talk) 23:33, 15 December 2007 (UTC)

[edit] Plagiarism

I've removed the plagiarism note from the page for two reasons-

  • There was no clearer and/or shorter way to state the same information, and so the wording would be the same.
  • Its been included as a reference and as such I don't think there should be a problem with keeping the info in.
Happy editing,xC | ☎ 14:54, 14 December 2007 (UTC)