PELI1

From Wikipedia, the free encyclopedia


Pellino homolog 1 (Drosophila)
Identifiers
Symbol(s) PELI1; DKFZp686C18116; MGC50990
External IDs MGI: 1914495 HomoloGene: 23243
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 57162 67245
Ensembl ENSG00000197329 ENSMUSG00000020134
Uniprot Q96FA3 Q3TJA0
Refseq NM_020651 (mRNA)
NP_065702 (protein)		 NM_030015 (mRNA)
NP_084291 (protein)
Location Chr 2: 64.17 - 64.23 Mb Chr 11: 20.99 - 21.05 Mb
Pubmed search [1] [2]

Pellino homolog 1 (Drosophila), also known as PELI1, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: PELI1 pellino homolog 1 (Drosophila).

[edit] Further reading

  • Rich T, Allen RL, Lucas AM, et al. (2001). "Pellino-related sequences from Caenorhabditis elegans and Homo sapiens.". Immunogenetics 52 (1-2): 145-9. PMID 11132151. 
  • Resch K, Jockusch H, Schmitt-John T (2001). "Assignment of homologous genes, Peli1/PELI1 and Peli2/PELI2, for the Pelle adaptor protein Pellino to mouse chromosomes 11 and 14 and human chromosomes 2p13.3 and 14q21, respectively, by physical and radiation hybrid mapping.". Cytogenet. Cell Genet. 92 (1-2): 172-4. PMID 11306823. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Jiang Z, Johnson HJ, Nie H, et al. (2003). "Pellino 1 is required for interleukin-1 (IL-1)-mediated signaling through its interaction with the IL-1 receptor-associated kinase 4 (IRAK4)-IRAK-tumor necrosis factor receptor-associated factor 6 (TRAF6) complex.". J. Biol. Chem. 278 (13): 10952-6. doi:10.1074/jbc.M212112200. PMID 12496252. 
  • Jensen LE, Whitehead AS (2003). "Pellino2 activates the mitogen activated protein kinase pathway.". FEBS Lett. 545 (2-3): 199-202. PMID 12804775. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Butler MP, Hanly JA, Moynagh PN (2005). "Pellino3 is a novel upstream regulator of p38 MAPK and activates CREB in a p38-dependent manner.". J. Biol. Chem. 280 (30): 27759-68. doi:10.1074/jbc.M500756200. PMID 15917247. 
  • Choi KC, Lee YS, Lim S, et al. (2006). "Smad6 negatively regulates interleukin 1-receptor-Toll-like receptor signaling through direct interaction with the adaptor Pellino-1.". Nat. Immunol. 7 (10): 1057-65. doi:10.1038/ni1383. PMID 16951688. 
  • Butler MP, Hanly JA, Moynagh PN (2007). "Kinase-active interleukin-1 receptor-associated kinases promote polyubiquitination and degradation of the Pellino family: direct evidence for PELLINO proteins being ubiquitin-protein isopeptide ligases.". J. Biol. Chem. 282 (41): 29729-37. doi:10.1074/jbc.M704558200. PMID 17675297. 
 This article on a gene on chromosome 2 is a stub. You can help Wikipedia by expanding it.