Peginterferon alfa-2a

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Peginterferon alfa-2a
Systematic (IUPAC) name
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Identifiers
CAS number 215647-85-1
ATC code L03AB11
PubChem  ?
DrugBank BTD00043
Chemical data
Formula C860H1353N227O255S9
Mol. mass 19241 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status

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Routes  ?

Pegylated interferon alfa-2a (40kD) (commercial name PEGASYS) is an antiviral drug discovered at the pharmaceutical company F.Hoffmann-La Roche; it has a dual mode of action - both antiviral and on the immune system.

This drug is approved around the world for the treatment of chronic hepatitis C (including patients with HIV co-infection, cirrhosis, 'normal' levels of ALT) and has recently been approved (in the EU, U.S., China and many other countries) for the treatment of chronic hepatitis B.

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