PECR

From Wikipedia, the free encyclopedia

Peroxisomal trans-2-enoyl-CoA reductase

PDB rendering based on 1yxm.

Available structures: 1yxm

Identifiers

Symbol(s)

PECR; HSA250303; TERP

External IDs

OMIM: 605843 MGI: 2148199 HomoloGene: 69255

Gene ontology
Molecular Function:	• oxidoreductase activity • trans-2-enoyl-CoA reductase (NADPH) activity
Cellular Component:	• mitochondrion • peroxisome
Biological Process:	• fatty acid biosynthetic process • metabolic process • regulation of apoptosis

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_018441 (mRNA)
NP_060911 (protein)

NM_023523 (mRNA)
NP_076012 (protein)

Location

Chr 2: 216.61 - 216.65 Mb

Chr 1: 72.19 - 72.22 Mb

Pubmed search

[1]

[2]

Peroxisomal trans-2-enoyl-CoA reductase, also known as PECR, is a human gene.^[1]

[edit] References

^ Entrez Gene: PECR peroxisomal trans-2-enoyl-CoA reductase.

[edit] Further reading

Das AK, Uhler MD, Hajra AK (2000). "Molecular cloning and expression of mammalian peroxisomal trans-2-enoyl-coenzyme A reductase cDNAs.". J. Biol. Chem. 275 (32): 24333-40. doi:10.1074/jbc.M001168200. PMID 10811639.
Gay F, Anglade I, Gong Z, Salbert G (2001). "The LIM/homeodomain protein islet-1 modulates estrogen receptor functions.". Mol. Endocrinol. 14 (10): 1627-48. PMID 11043578.
Amery L, Mannaerts GP, Subramani S, et al. (2001). "Identification of a novel human peroxisomal 2,4-dienoyl-CoA reductase related protein using the M13 phage protein VI phage display technology.". Comb. Chem. High Throughput Screen. 4 (7): 545-52. PMID 11669066.
Jia L, Young MF, Powell J, et al. (2002). "Gene expression profile of human bone marrow stromal cells: high-throughput expressed sequence tag sequencing analysis.". Genomics 79 (1): 7-17. doi:10.1006/geno.2001.6683. PMID 11827452.
Braastad CD, Leguia M, Hendrickson EA (2002). "Ku86 autoantigen related protein-1 transcription initiates from a CpG island and is induced by p53 through a nearby p53 response element.". Nucleic Acids Res. 30 (8): 1713-24. PMID 11937624.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724-31. doi:10.1038/nature03466. PMID 15815621.
Gloerich J, Ruiter JP, van den Brink DM, et al. (2006). "Peroxisomal trans-2-enoyl-CoA reductase is involved in phytol degradation.". FEBS Lett. 580 (8): 2092-6. doi:10.1016/j.febslet.2006.03.011. PMID 16546181.