PDZK1

From Wikipedia, the free encyclopedia

PDZ domain containing 1

Identifiers

PDZK1; CAP70; CLAMP; PDZD1

External IDs

OMIM: 603831 MGI: 1928901 HomoloGene: 1964

Gene ontology
Molecular Function:	• transporter activity • protein binding • protein C-terminus binding • PDZ domain binding
Biological Process:	• cell proliferation • drug transport

Orthologs

Human

Mouse

n/a

n/a

Refseq

XM_001126677 (mRNA)
XP_001126677 (protein)

NM_021517 (mRNA)
NP_067492 (protein)

Location

n/a

Chr 3: 96.94 - 96.96 Mb

Pubmed search

[1]

[2]

PDZ domain containing 1, also known as PDZK1, is a human gene.^[1]

[edit] References

^ Entrez Gene: PDZK1 PDZ domain containing 1.

[edit] Further reading

Kocher O, Comella N, Tognazzi K, Brown LF (1998). "Identification and partial characterization of PDZK1: a novel protein containing PDZ interaction domains.". Lab. Invest. 78 (1): 117–25. PMID 9461128.
White KE, Biber J, Murer H, Econs MJ (1999). "A PDZ domain-containing protein with homology to Diphor-1 maps to human chromosome 1q21.". Ann. Hum. Genet. 62 (Pt 4): 287–90. doi:10.1046/j.1469-1809.1998.6240287.x. PMID 9924606.
Kocher O, Comella N, Gilchrist A, et al. (1999). "PDZK1, a novel PDZ domain-containing protein up-regulated in carcinomas and mapped to chromosome 1q21, interacts with cMOAT (MRP2), the multidrug resistance-associated protein.". Lab. Invest. 79 (9): 1161–70. PMID 10496535.
Ikemoto M, Arai H, Feng D, et al. (2000). "Identification of a PDZ-domain-containing protein that interacts with the scavenger receptor class B type I.". Proc. Natl. Acad. Sci. U.S.A. 97 (12): 6538–43. doi:10.1073/pnas.100114397. PMID 10829064.
Wang S, Yue H, Derin RB, et al. (2000). "Accessory protein facilitated CFTR-CFTR interaction, a molecular mechanism to potentiate the chloride channel activity.". Cell 103 (1): 169–79. PMID 11051556.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMID 11076863.
Gisler SM, Stagljar I, Traebert M, et al. (2001). "Interaction of the type IIa Na/Pi cotransporter with PDZ proteins.". J. Biol. Chem. 276 (12): 9206–13. doi:10.1074/jbc.M008745200. PMID 11099500.
Silver DL (2002). "A carboxyl-terminal PDZ-interacting domain of scavenger receptor B, type I is essential for cell surface expression in liver.". J. Biol. Chem. 277 (37): 34042–7. doi:10.1074/jbc.M206584200. PMID 12119305.
Sellin L, Huber TB, Gerke P, et al. (2003). "NEPH1 defines a novel family of podocin interacting proteins.". FASEB J. 17 (1): 115–7. doi:10.1096/fj.02-0242fje. PMID 12424224.
Gentzsch M, Cui L, Mengos A, et al. (2003). "The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins.". J. Biol. Chem. 278 (8): 6440–9. doi:10.1074/jbc.M211050200. PMID 12471024.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Hegedüs T, Sessler T, Scott R, et al. (2003). "C-terminal phosphorylation of MRP2 modulates its interaction with PDZ proteins.". Biochem. Biophys. Res. Commun. 302 (3): 454–61. PMID 12615054.
Silver DL, Wang N, Vogel S (2003). "Identification of small PDZK1-associated protein, DD96/MAP17, as a regulator of PDZK1 and plasma high density lipoprotein levels.". J. Biol. Chem. 278 (31): 28528–32. doi:10.1074/jbc.M304109200. PMID 12754212.
Pribanic S, Gisler SM, Bacic D, et al. (2003). "Interactions of MAP17 with the NaPi-IIa/PDZK1 protein complex in renal proximal tubular cells.". Am. J. Physiol. Renal Physiol. 285 (4): F784–91. doi:10.1152/ajprenal.00109.2003. PMID 12837682.
Gisler SM, Pribanic S, Bacic D, et al. (2004). "PDZK1: I. a major scaffolder in brush borders of proximal tubular cells.". Kidney Int. 64 (5): 1733–45. doi:10.1046/j.1523-1755.2003.00266.x. PMID 14531806.
Kocher O, Yesilaltay A, Cirovic C, et al. (2004). "Targeted disruption of the PDZK1 gene in mice causes tissue-specific depletion of the high density lipoprotein receptor scavenger receptor class B type I and altered lipoprotein metabolism.". J. Biol. Chem. 278 (52): 52820–5. doi:10.1074/jbc.M310482200. PMID 14551195.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Inoue J, Otsuki T, Hirasawa A, et al. (2004). "Overexpression of PDZK1 within the 1q12-q22 amplicon is likely to be associated with drug-resistance phenotype in multiple myeloma.". Am. J. Pathol. 165 (1): 71–81. PMID 15215163.
Anzai N, Miyazaki H, Noshiro R, et al. (2004). "The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus.". J. Biol. Chem. 279 (44): 45942–50. doi:10.1074/jbc.M406724200. PMID 15304510.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.