PDS5B

From Wikipedia, the free encyclopedia

Androgen-induced proliferation inhibitor

Identifiers

APRIN; AS3; CG008; FLJ23236; KIAA0979; PDS5B; RP1-267P19.1

External IDs

OMIM: 605333 MGI: 2140945 HomoloGene: 41001

Gene ontology
Molecular Function:	• DNA binding • ATP binding • transferase activity, transferring hexosyl groups
Cellular Component:	• nucleus • membrane
Biological Process:	• carbohydrate metabolic process • negative regulation of cell proliferation

Orthologs

Human

Mouse

Refseq

NM_015032 (mRNA)
NP_055847 (protein)

XM_622918 (mRNA)
XP_622918 (protein)

Location

Chr 13: 32.06 - 32.25 Mb

Chr 5: 150.94 - 151.08 Mb

Pubmed search

[1]

[2]

Androgen-induced proliferation inhibitor, also known as APRIN, is a human gene.^[1]

[edit] References

^ Entrez Gene: APRIN androgen-induced proliferation inhibitor.

[edit] Further reading

Couch FJ, Rommens JM, Neuhausen SL, et al. (1997). "Generation of an integrated transcription map of the BRCA2 region on chromosome 13q12-q13.". Genomics 36 (1): 86-99. PMID 8812419.
Geck P, Szelei J, Jimenez J, et al. (1999). "Early gene expression during androgen-induced inhibition of proliferation of prostate cancer cells: a new suppressor candidate on chromosome 13, in the BRCA2-Rb1 locus.". J. Steroid Biochem. Mol. Biol. 68 (1-2): 41-50. PMID 10215036.
Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 6 (1): 63-70. PMID 10231032.
Geck P, Maffini MV, Szelei J, et al. (2000). "Androgen-induced proliferative quiescence in prostate cancer cells: the role of AS3 as its mediator.". Proc. Natl. Acad. Sci. U.S.A. 97 (18): 10185-90. PMID 10963680.
Maffini MV, Geck P, Powell CE, et al. (2002). "Mechanism of androgen action on cell proliferation: AS3 protein as a mediator of proliferative arrest in the rat prostate.". Endocrinology 143 (7): 2708-14. PMID 12072405.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130-5. doi:10.1073/pnas.0404720101. PMID 15302935.
Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain.". Mol. Cell Proteomics 3 (11): 1093-101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
Rankin S, Ayad NG, Kirschner MW (2005). "Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates.". Mol. Cell 18 (2): 185-200. doi:10.1016/j.molcel.2005.03.017. PMID 15837422.
Losada A, Yokochi T, Hirano T (2006). "Functional contribution of Pds5 to cohesin-mediated cohesion in human cells and Xenopus egg extracts.". J. Cell. Sci. 118 (Pt 10): 2133-41. doi:10.1242/jcs.02355. PMID 15855230.