PDE6C

From Wikipedia, the free encyclopedia

Phosphodiesterase 6C, cGMP-specific, cone, alpha prime

Identifiers

External IDs

OMIM: 600827 MGI: 105956 HomoloGene: 4521

Gene ontology
Molecular Function:	• hydrolase activity • 3',5'-cyclic-GMP phosphodiesterase activity
Cellular Component:	• membrane
Biological Process:	• signal transduction • visual perception • response to stimulus

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_006204 (mRNA)
NP_006195 (protein)

NM_033614 (mRNA)
NP_291092 (protein)

Location

n/a

Chr 19: 38.2 - 38.25 Mb

Pubmed search

[1]

[2]

Phosphodiesterase 6C, cGMP-specific, cone, alpha prime, also known as PDE6C, is a human gene.^[1]

[edit] References

^ Entrez Gene: PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime.

[edit] Further reading

Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10.". Nature 429 (6990): 375-81. doi:10.1038/nature02462. PMID 15164054.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Bertazolli-Filho R, Ghosh S, Huang W, et al. (2001). "Molecular evidence that human ocular ciliary epithelium expresses components involved in phototransduction.". Biochem. Biophys. Res. Commun. 284 (2): 317-25. doi:10.1006/bbrc.2001.4970. PMID 11394879.
Harrington JJ, Sherf B, Rundlett S, et al. (2001). "Creation of genome-wide protein expression libraries using random activation of gene expression.". Nat. Biotechnol. 19 (5): 440-5. doi:10.1038/88107. PMID 11329013.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788-95. PMID 11076863.
Gao YQ, Danciger M, Longmuir R, et al. (1999). "Screening of the gene encoding the alpha'-subunit of cone cGMP-PDE in patients with retinal degenerations.". Invest. Ophthalmol. Vis. Sci. 40 (8): 1818-22. PMID 10393054.
Feshchenko EA, Andreeva SG, Suslova VA, et al. (1996). "Human cone-specific cGMP phosphodiesterase alpha' subunit: complete cDNA sequence and gene arrangement.". FEBS Lett. 381 (1-2): 149-52. PMID 8641425.
Viczian AS, Piriev NI, Farber DB (1996). "Isolation and characterization of a cDNA encoding the alpha' subunit of human cone cGMP-phosphodiesterase.". Gene 166 (2): 205-11. PMID 8543163.
Piriev NI, Viczian AS, Ye J, et al. (1996). "Gene structure and amino acid sequence of the human cone photoreceptor cGMP-phosphodiesterase alpha' subunit (PDEA2) and its chromosomal localization to 10q24.". Genomics 28 (3): 429-35. doi:10.1006/geno.1995.1171. PMID 7490077.