PDE1C

From Wikipedia, the free encyclopedia

Phosphodiesterase 1C, calmodulin-dependent 70kDa

Identifiers

External IDs

OMIM: 602987 MGI: 108413 HomoloGene: 3682

Gene ontology
Molecular Function:	• catalytic activity • 3',5'-cyclic-nucleotide phosphodiesterase activity • calmodulin-dependent cyclic-nucleotide phosphodiesterase activity • calmodulin binding • hydrolase activity
Biological Process:	• signal transduction

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_005020 (mRNA)
NP_005011 (protein)

NM_001025568 (mRNA)
NP_001020739 (protein)

Location

Chr 7: 31.76 - 32.3 Mb

Chr 6: 56 - 56.29 Mb

Pubmed search

[1]

[2]

Phosphodiesterase 1C, calmodulin-dependent 70kDa, also known as PDE1C, is a human gene.^[1]

[edit] References

^ Entrez Gene: PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa.

[edit] Further reading

Vandeput F, Wolda SL, Krall J, et al. (2007). "Cyclic nucleotide phosphodiesterase PDE1C1 in human cardiac myocytes.". J. Biol. Chem. 282 (45): 32749-57. doi:10.1074/jbc.M703173200. PMID 17726023.
Dolci S, Belmonte A, Santone R, et al. (2006). "Subcellular localization and regulation of type-1C and type-5 phosphodiesterases.". Biochem. Biophys. Res. Commun. 341 (3): 837-46. doi:10.1016/j.bbrc.2006.01.035. PMID 16455054.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157-64. doi:10.1038/nature01782. PMID 12853948.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Rybalkin SD, Rybalkina I, Beavo JA, Bornfeldt KE (2002). "Cyclic nucleotide phosphodiesterase 1C promotes human arterial smooth muscle cell proliferation.". Circ. Res. 90 (2): 151-7. PMID 11834707.
Yan C, Zhao AZ, Sonnenburg WK, Beavo JA (2001). "Stage and cell-specific expression of calmodulin-dependent phosphodiesterases in mouse testis.". Biol. Reprod. 64 (6): 1746-54. PMID 11369604.
Zauli G, Milani D, Mirandola P, et al. (2001). "HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway.". FASEB J. 15 (2): 483-91. doi:10.1096/fj.00-0354com. PMID 11156964.
Loughney K, Martins TJ, Harris EA, et al. (1996). "Isolation and characterization of cDNAs corresponding to two human calcium, calmodulin-regulated, 3',5'-cyclic nucleotide phosphodiesterases.". J. Biol. Chem. 271 (2): 796-806. PMID 8557689.