PDCD7

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Programmed cell death 7
Identifiers
Symbol(s) PDCD7; ES18; HES18; MGC22015
External IDs OMIM: 608138 MGI: 1859170 HomoloGene: 4170
Orthologs
Human Mouse
Entrez 10081 50996
Ensembl ENSG00000090470 ENSMUSG00000041837
Uniprot Q8N8D1 Q3U2X6
Refseq NM_005707 (mRNA)
NP_005698 (protein)		 XM_001003772 (mRNA)
XP_001003772 (protein)
Location Chr 15: 63.2 - 63.21 Mb Chr 9: 65.14 - 65.16 Mb
Pubmed search [1] [2]

Programmed cell death 7, also known as PDCD7, is a human gene.[1]

This gene encodes a protein with sequence similarity to a mouse protein originally identified in embryonic stem cells. In mouse T-cell lines, this protein appears to be related to glucocorticoid- and staurine-induced apoptotic pathways, and to be linked to ceramide-mediated signalling. These observations suggest that this gene product is involved in specific apoptotic processes in T-cells.[1]

[edit] References

  1. ^ a b Entrez Gene: PDCD7 programmed cell death 7.

[edit] Further reading

  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway.". Genome Res. 14 (7): 1324-32. doi:10.1101/gr.2334104. PMID 15231748. 
  • Will CL, Schneider C, Hossbach M, et al. (2004). "The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome.". RNA 10 (6): 929-41. PMID 15146077. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Park EJ, Kim JH, Seong RH, et al. (1999). "Characterization of a novel mouse cDNA, ES18, involved in apoptotic cell death of T-cells.". Nucleic Acids Res. 27 (6): 1524-30. PMID 10037816. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149. 
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298. 
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