PCYT1B

From Wikipedia, the free encyclopedia

Phosphate cytidylyltransferase 1, choline, beta

Identifiers

PCYT1B; CTB; CCT-beta

External IDs

OMIM: 604926 MGI: 2147987 HomoloGene: 3564

Gene ontology
Molecular Function:	• choline-phosphate cytidylyltransferase activity • transferase activity
Cellular Component:	• cytoplasm • endoplasmic reticulum
Biological Process:	• ovarian follicle development • phosphatidylcholine biosynthetic process • spermatogenesis • phospholipid biosynthetic process • biosynthetic process

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_004845 (mRNA)
NP_004836 (protein)

NM_177546 (mRNA)
NP_808214 (protein)

Location

Chr X: 24.49 - 24.6 Mb

Chr X: 89.93 - 90 Mb

Pubmed search

[1]

[2]

Phosphate cytidylyltransferase 1, choline, beta, also known as PCYT1B, is a human gene.^[1]

[edit] References

^ Entrez Gene: PCYT1B phosphate cytidylyltransferase 1, choline, beta.

[edit] Further reading

Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain.". Mol. Cell Proteomics 3 (11): 1093-101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Llorca O, Martín-Benito J, Gómez-Puertas P, et al. (2002). "Analysis of the interaction between the eukaryotic chaperonin CCT and its substrates actin and tubulin.". J. Struct. Biol. 135 (2): 205-18. doi:10.1006/jsbi.2001.4359. PMID 11580270.
McCormack EA, Llorca O, Carrascosa JL, et al. (2002). "Point mutations in a hinge linking the small and large domains of beta-actin result in trapped folding intermediates bound to cytosolic chaperonin CCT.". J. Struct. Biol. 135 (2): 198-204. doi:10.1006/jsbi.2001.4385. PMID 11580269.
Lykidis A, Baburina I, Jackowski S (1999). "Distribution of CTP:phosphocholine cytidylyltransferase (CCT) isoforms. Identification of a new CCTbeta splice variant.". J. Biol. Chem. 274 (38): 26992-7001. PMID 10480912.
Gubin AN, Njoroge JM, Bouffard GG, Miller JL (1999). "Gene expression in proliferating human erythroid cells.". Genomics 59 (2): 168-77. doi:10.1006/geno.1999.5855. PMID 10409428.
Lykidis A, Murti KG, Jackowski S (1998). "Cloning and characterization of a second human CTP:phosphocholine cytidylyltransferase.". J. Biol. Chem. 273 (22): 14022-9. PMID 9593753.