PBX3

From Wikipedia, the free encyclopedia


Pre-B-cell leukemia homeobox 3
PDB rendering based on 1b72.
Available structures: 1b72, 1b8i, 1du6, 1lfu, 1puf
Identifiers
Symbol(s) PBX3;
External IDs OMIM: 176312 MGI97496 HomoloGene21243
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 5090 18516
Ensembl ENSG00000167081 ENSMUSG00000038718
Uniprot P40426 O35317
Refseq NM_006195 (mRNA)
NP_006186 (protein)
XM_992943 (mRNA)
XP_998037 (protein)
Location Chr 9: 127.55 - 127.77 Mb Chr 2: 33.99 - 34.19 Mb
Pubmed search [1] [2]

Pre-B-cell leukemia homeobox 3, also known as PBX3, is a human gene.[1]


[edit] References

[edit] Further reading

  • Monica K, Galili N, Nourse J, et al. (1991). "PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1.". Mol. Cell. Biol. 11 (12): 6149-57. PMID 1682799. 
  • Lu Q, Wright DD, Kamps MP (1994). "Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation.". Mol. Cell. Biol. 14 (6): 3938-48. PMID 7910944. 
  • Shen WF, Rozenfeld S, Kwong A, et al. (1999). "HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells.". Mol. Cell. Biol. 19 (4): 3051-61. PMID 10082572. 
  • Fujino T, Yamazaki Y, Largaespada DA, et al. (2001). "Inhibition of myeloid differentiation by Hoxa9, Hoxb8, and Meis homeobox genes.". Exp. Hematol. 29 (7): 856-63. PMID 11438208. 
  • Knoepfler PS, Sykes DB, Pasillas M, Kamps MP (2001). "HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation.". Oncogene 20 (39): 5440-8. doi:10.1038/sj.onc.1204710. PMID 11571641. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9.". Nature 429 (6990): 369-74. doi:10.1038/nature02465. PMID 15164053. 
  • Rhee JW, Arata A, Selleri L, et al. (2004). "Pbx3 deficiency results in central hypoventilation.". Am. J. Pathol. 165 (4): 1343-50. PMID 15466398. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514. 

[edit] External links


This article incorporates text from the United States National Library of Medicine, which is in the public domain.