Talk:Patch clamp
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[edit] Source of orginal content
Most of this article was cut-and-pasted on Feb 22, 2005 from the voltage clamp article as part of an attempt to clean up that article. Anyone interested in the history of this article should therefore look at the voltage clamp history page prior to that date. I did not write this article. I have a limited knowledge of electrophysiology, but I believe there are several errors in the article. I will try to fix them to the best of my ability, but it may take a few days. Sayeth 21:55, 22 February 2006 (UTC)
- Fixed errors, as far as I know, and added image. If anyone has an actual picture of a patch clamped cell, that would be great for the intro portion. Sayeth 20:21, 17 March 2006 (UTC)
- Added Whole-cell to outside-out diagram 12/06/2007 Schmoozy —Preceding comment was added at 19:57, 6 December 2007 (UTC)
[edit] Page name?
This technique is commonly known as "Patch Clamping" or "To Patch Clamp". However, the term "Patch Clamp" is also commonly taken to mean the specific instrument with which you "Patch".
See http://www.cairn-research.co.uk/systems/prod_patch1.html or http://www.moleculardevices.com/pages/instruments/cn_axopatch200b.html For examples of Patch Clamps.
[edit] Perforated patch
Not sure if I agree with the perforated patch section: I've recorded for several hours with gramicidin perforations without any obvious loss of the cell's properties, ie. longer than in whole-cell configuration. Would be nice to see a source for this statement? —Preceding unsigned comment added by 80.229.216.34 (talk) 19:04, 21 February 2008 (UTC)
