Patulin

From Wikipedia, the free encyclopedia

Patulin[1]
IUPAC name 2-Hydroxy-3,7-dioxabicyclo
[4.3.0]nona-5,9-dien-8-one
Other names Clairformin
Claviform
Expansine
Clavacin
Clavatin
Expansin
Gigantin
Leucopin
Patuline
Identifiers
CAS number [149-29-1]
PubChem 4696
EINECS number 205-735-2
SMILES C1C=C2C(=CC(=O)O2)C(O1)O
Properties
Molecular formula C7H6O4
Molar mass 154.12 g/mol
Appearance Compact prisms
Melting point

110 °C, 383 K, 230 °F

Solubility in water Soluble
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Patulin is a mycotoxin produced by a variety of molds, particularly Aspergillus and Penicillium. It is commonly found in rotting apples, and the amount of patulin in apple products is generally viewed as a measure of the quality of the apples used in production. It is not a particularly potent toxin, but a number of studies have shown that it is genotoxic, which has led to some theories that it may be a carcinogen, though animal studies have remained inconclusive.[2] Patulin is also an antibiotic.[1] Several countries have instituted patulin restrictions in apple products. The World Health Organization recommends a maximum concentration of 50 µg/L in apple juice.[3]

[edit] References

  1. ^ a b Merck Index, 11th Edition, 7002.
  2. ^ "Patulin: a Mycotoxin in Apples" (August 1997). Perishables Handling Quarterly (91): 5. 
  3. ^ Foodborne hazards (World Health Organization. Retrieved on 2007-01-22.

[edit] External links