Patulin
From Wikipedia, the free encyclopedia
Patulin[1] | |
---|---|
IUPAC name | 2-Hydroxy-3,7-dioxabicyclo [4.3.0]nona-5,9-dien-8-one |
Other names | Clairformin Claviform Expansine Clavacin Clavatin Expansin Gigantin Leucopin Patuline |
Identifiers | |
CAS number | [149-29-1] |
PubChem | |
EINECS number | |
SMILES | C1C=C2C(=CC(=O)O2)C(O1)O |
Properties | |
Molecular formula | C7H6O4 |
Molar mass | 154.12 g/mol |
Appearance | Compact prisms |
Melting point |
110 °C, 383 K, 230 °F |
Solubility in water | Soluble |
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
Patulin is a mycotoxin produced by a variety of molds, particularly Aspergillus and Penicillium. It is commonly found in rotting apples, and the amount of patulin in apple products is generally viewed as a measure of the quality of the apples used in production. It is not a particularly potent toxin, but a number of studies have shown that it is genotoxic, which has led to some theories that it may be a carcinogen, though animal studies have remained inconclusive.[2] Patulin is also an antibiotic.[1] Several countries have instituted patulin restrictions in apple products. The World Health Organization recommends a maximum concentration of 50 µg/L in apple juice.[3]
[edit] References
- ^ a b Merck Index, 11th Edition, 7002.
- ^ "Patulin: a Mycotoxin in Apples" (August 1997). Perishables Handling Quarterly (91): 5.
- ^ Foodborne hazards (World Health Organization. Retrieved on 2007-01-22.