Paterno-Buchi reaction
From Wikipedia, the free encyclopedia
The Paternò–Büchi reaction, named after Emanuele Paternò and George Hermann Büchi who established its basic utility and form, is a photochemical reaction that forms four-membered oxetane rings from a carbonyl and an alkene. [1] [2]
Much work has been done with the reaction since Dr. Thorsten Bach of the University of Marburg published a review article in 1998 on its mechanism and synthetic utility.[3]
The Paternò–Büchi reaction has been used recently in attempt to synthesize many natural organic products. In these experiments, the chemists are chiefly concerned with the regio- and diastereoselectivity of the products.
[edit] References
- ^ E. Paterno, G. Chieffi (1909). ".". Gazz. Chim. Ital. 39: 341.
- ^ G. Büchi, Charles G. Inman, and E. S. Lipinsky (1954). "Light-catalyzed Organic Reactions. I. The Reaction of Carbonyl Compounds with 2-Methyl-2-butene in the Presence of Ultraviolet Light". Journal of the American Chemical Society 76 (17): 4327–4331. doi:.
- ^ Thorsten Bach (1998). "Stereoselective Intermolecular [2 + 2]-Photocycloaddition Reactions and Their Application in Synthesis". Synthesis 1998: 683–703. doi:.
