para-Aminohippurate
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| Para-Aminohippurate | |
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| IUPAC name | sodium 2-[(4-aminobenzoyl)amino]acetate |
| Identifiers | |
| CAS number | |
| PubChem | |
| SMILES | C1=CC(=CC=C1C(=O)NCC(=O)[O-])N.[Na+] |
| Properties | |
| Molecular formula | C9H9N2NaO3 |
| Molar mass | 216.169 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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para-Aminohippurate (PAH) is a substance used in the measurement of renal blood flow. It is useful in this measurement because it is primarily secreted by the renal tubules; only 20-30% is filtered by the glomerulus.[1]
The renal extraction ratio of PAH is a normal individual is approximately 0.92.[2]
[edit] References
- ^ Phillips, R. A.; P. B. Hamilton (1948-02-29). "Effect of 20,60 and 120 minutes of renal ischemia on glomerular and tubular function" (PDF). Am J Physiol 152 (3): 523–30. ISSN 0002-9513.
- ^ Reubi, François C. (1953-04-29). "Glomerular filtration rate, renal blood flow and blood viscosity during and after diabetic coma". Circ. Res. 1 (5): 410–3. ISSN 00097330. PMID 13082682.
[edit] Further reading
[edit] External links
- "Effect of 20,60 and 120 minutes of renal ischemia on glomerular and tubular function" (subscription may be necessary)
- "Glomerular filtration rate, renal blood flow and blood viscosity during and after diabetic coma" (subscription may be necessary)
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