PARD3B

From Wikipedia, the free encyclopedia

Par-3 partitioning defective 3 homolog B (C. elegans)

PDB rendering based on 1wg6.

Available structures: 1wg6

Identifiers

Symbol(s)

PARD3B; ALS2CR19; MGC16131; PAR3B; PAR3L; PAR3LC; PAR3beta; Par3Lb

External IDs

MGI: 1919301 HomoloGene: 35389

Gene ontology
Molecular Function:	• protein binding
Cellular Component:	• tight junction • membrane
Biological Process:	• cell cycle • cell division

Orthologs

Human

Mouse

Refseq

NM_057177 (mRNA)
NP_476518 (protein)

XM_110852 (mRNA)
XP_110852 (protein)

Location

Chr 2: 205.12 - 206.19 Mb

Chr 1: 61.57 - 62.57 Mb

Pubmed search

[1]

[2]

Par-3 partitioning defective 3 homolog B (C. elegans), also known as PARD3B, is a human gene.^[1]

[edit] References

^ Entrez Gene: PARD3B par-3 partitioning defective 3 homolog B (C. elegans).

[edit] Further reading

Izaki T, Kamakura S, Kohjima M, Sumimoto H (2006). "Two forms of human Inscuteable-related protein that links Par3 to the Pins homologues LGN and AGS3.". Biochem. Biophys. Res. Commun. 341 (4): 1001-6. doi:10.1016/j.bbrc.2006.01.050. PMID 16458856.
Benzinger A, Muster N, Koch HB, et al. (2005). "Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.". Mol. Cell Proteomics 4 (6): 785-95. doi:10.1074/mcp.M500021-MCP200. PMID 15778465.
Izaki T, Kamakura S, Kohjima M, Sumimoto H (2005). "Phosphorylation-dependent binding of 14-3-3 to Par3beta, a human Par3-related cell polarity protein.". Biochem. Biophys. Res. Commun. 329 (1): 211-8. doi:10.1016/j.bbrc.2005.01.115. PMID 15721295.
Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.". Curr. Biol. 14 (16): 1436-50. doi:10.1016/j.cub.2004.07.051. PMID 15324660.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Warner DR, Pisano MM, Roberts EA, Greene RM (2003). "Identification of three novel Smad binding proteins involved in cell polarity.". FEBS Lett. 539 (1-3): 167-73. PMID 12650946.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Kohjima M, Noda Y, Takeya R, et al. (2003). "PAR3beta, a novel homologue of the cell polarity protein PAR3, localizes to tight junctions.". Biochem. Biophys. Res. Commun. 299 (4): 641-6. PMID 12459187.
Gao L, Macara IG, Joberty G (2003). "Multiple splice variants of Par3 and of a novel related gene, Par3L, produce proteins with different binding properties.". Gene 294 (1-2): 99-107. PMID 12234671.
Hadano S, Hand CK, Osuga H, et al. (2001). "A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2.". Nat. Genet. 29 (2): 166-73. doi:10.1038/ng1001-166. PMID 11586298.