Oxalate oxidase
From Wikipedia, the free encyclopedia
In enzymology, an oxalate oxidase (EC 1.2.3.4) is an enzyme that catalyzes the chemical reaction
- oxalate + O2 + 2 H+ 2 CO2 + H2O2
The 3 substrates of this enzyme are oxalate, O2, and H+, whereas its two products are CO2 and H2O2.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with oxygen as acceptor. The systematic name of this enzyme class is oxalate:oxygen oxidoreductase. Other names in common use include aero-oxalo dehydrogenase, and oxalic acid oxidase. This enzyme participates in glyoxylate and dicarboxylate metabolism. It has 2 cofactors: FAD, and Manganese.
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[edit] Structural studies
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 1FI2, 2ET1, 2ET7, and 2ETE.
[edit] References
- IUBMB entry for 1.2.3.4
- BRENDA references for 1.2.3.4 (Recommended.)
- PubMed references for 1.2.3.4
- PubMed Central references for 1.2.3.4
- Google Scholar references for 1.2.3.4
- DATTA PK, MEEUSE BJ (1955). "Moss oxalic acid oxidase-a flavoprotein". Biochim. Biophys. Acta. 17: 602–3. doi: . PMID 13250021.
- Kotsira VP, Clonis YD (1997). "Oxalate oxidase from barley roots: purification to homogeneity and study of some molecular, catalytic, and binding properties". Arch. Biochem. Biophys. 340: 239–49. doi: . PMID 9143327.
- Requena L, Bornemann S (1999). "Barley (Hordeum vulgare) oxalate oxidase is a manganese-containing enzyme". Biochem. J. 343 Pt 1: 185–90. PMID 10493928.
[edit] External links
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- The CAS registry number for this enzyme class is 9031-79-2.