Oxalate-CoA ligase

From Wikipedia, the free encyclopedia

In enzymology, an oxalate-CoA ligase (EC 6.2.1.8) is an enzyme that catalyzes the chemical reaction

ATP + oxalate + CoA AMP + diphosphate + oxalyl-CoA

The 3 substrates of this enzyme are ATP, oxalate, and CoA, whereas its 3 products are AMP, diphosphate, and oxalyl-CoA.

This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is oxalate:CoA ligase (AMP-forming). Other names in common use include oxalyl-CoA synthetase, and oxalyl coenzyme A synthetase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

[edit] References

• IUBMB entry for 6.2.1.8
• BRENDA references for 6.2.1.8 (Recommended.)
• PubMed references for 6.2.1.8
• PubMed Central references for 6.2.1.8
• Google Scholar references for 6.2.1.8
• Giovanelli J (1966). "Oxalyl-coenzyme A synthetase from pea seeds". Biochim. Biophys. Acta. 118: 124–43. PMID 4288975. 

[edit] External links

The CAS registry number for this enzyme class is 37318-57-3.

• IUBMB entry for 6.2.1.8

• KEGG entry for 6.2.1.8

• BRENDA entry for 6.2.1.8

• NiceZyme view of 6.2.1.8

• EC2PDB: PDB structures for 6.2.1.8

• PRIAM entry for 6.2.1.8

• PUMA2 entry for 6.2.1.8

• IntEnz: Integrated Enzyme entry for 6.2.1.8

• MetaCyc entry for 6.2.1.8

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050203: oxalate-CoA ligase

• AMIGO entry for GO code 0050203: oxalate-CoA ligase