OSTbeta

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Organic solute transporter beta
Identifiers
Symbol(s) OSTbeta; FLJ26090; MGC118959; MGC118960; MGC118961
External IDs MGI: 3582052 HomoloGene: 18721
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 123264 330962
Ensembl ENSG00000186198 ENSMUSG00000053862
Refseq NM_178859 (mRNA)
NP_849190 (protein)		 NM_178933 (mRNA)
NP_849264 (protein)
Location Chr 15: 63.12 - 63.13 Mb Chr 9: 65.21 - 65.22 Mb
Pubmed search [1] [2]

Organic solute transporter beta, also known as OSTbeta, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: OSTbeta organic solute transporter beta.

[edit] Further reading

  • Sun AQ, Balasubramaniyan N, Xu K, et al. (2007). "Protein-protein interactions and membrane localization of the human organic solute transporter.". Am. J. Physiol. Gastrointest. Liver Physiol. 292 (6): G1586-93. doi:10.1152/ajpgi.00457.2006. PMID 17332473. 
  • Boyer JL, Trauner M, Mennone A, et al. (2006). "Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents.". Am. J. Physiol. Gastrointest. Liver Physiol. 290 (6): G1124-30. doi:10.1152/ajpgi.00539.2005. PMID 16423920. 
  • Ballatori N, Christian WV, Lee JY, et al. (2005). "OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia.". Hepatology 42 (6): 1270-9. doi:10.1002/hep.20961. PMID 16317684. 
  • Landrier JF, Eloranta JJ, Vavricka SR, Kullak-Ublick GA (2006). "The nuclear receptor for bile acids, FXR, transactivates human organic solute transporter-alpha and -beta genes.". Am. J. Physiol. Gastrointest. Liver Physiol. 290 (3): G476-85. doi:10.1152/ajpgi.00430.2005. PMID 16269519. 
  • Lee H, Zhang Y, Lee FY, et al. (2006). "FXR regulates organic solute transporters alpha and beta in the adrenal gland, kidney, and intestine.". J. Lipid Res. 47 (1): 201-14. doi:10.1194/jlr.M500417-JLR200. PMID 16251721. 
  • Dawson PA, Hubbert M, Haywood J, et al. (2005). "The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter.". J. Biol. Chem. 280 (8): 6960-8. doi:10.1074/jbc.M412752200. PMID 15563450. 
  • Seward DJ, Koh AS, Boyer JL, Ballatori N (2003). "Functional complementation between a novel mammalian polygenic transport complex and an evolutionarily ancient organic solute transporter, OSTalpha-OSTbeta.". J. Biol. Chem. 278 (30): 27473-82. doi:10.1074/jbc.M301106200. PMID 12719432. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
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