OSTalpha

From Wikipedia, the free encyclopedia


Organic solute transporter alpha
Identifiers
Symbol(s) OSTalpha; MGC39807
External IDs MGI: 2146634 HomoloGene: 44941
Orthologs
Human Mouse
Entrez 200931 106407
Ensembl ENSG00000163959 ENSMUSG00000035699
Refseq NM_152672 (mRNA)
NP_689885 (protein)		 NM_145932 (mRNA)
NP_666044 (protein)
Location Chr 3: 197.43 - 197.44 Mb Chr 16: 32.4 - 32.41 Mb
Pubmed search [1] [2]

Organic solute transporter alpha, also known as OSTalpha, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: OSTalpha organic solute transporter alpha.

[edit] Further reading

  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Seward DJ, Koh AS, Boyer JL, Ballatori N (2003). "Functional complementation between a novel mammalian polygenic transport complex and an evolutionarily ancient organic solute transporter, OSTalpha-OSTbeta.". J. Biol. Chem. 278 (30): 27473–82. doi:10.1074/jbc.M301106200. PMID 12719432. 
  • Dawson PA, Hubbert M, Haywood J, et al. (2005). "The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter.". J. Biol. Chem. 280 (8): 6960–8. doi:10.1074/jbc.M412752200. PMID 15563450. 
  • Lee H, Zhang Y, Lee FY, et al. (2006). "FXR regulates organic solute transporters alpha and beta in the adrenal gland, kidney, and intestine.". J. Lipid Res. 47 (1): 201–14. doi:10.1194/jlr.M500417-JLR200. PMID 16251721. 
  • Landrier JF, Eloranta JJ, Vavricka SR, Kullak-Ublick GA (2006). "The nuclear receptor for bile acids, FXR, transactivates human organic solute transporter-alpha and -beta genes.". Am. J. Physiol. Gastrointest. Liver Physiol. 290 (3): G476–85. doi:10.1152/ajpgi.00430.2005. PMID 16269519. 
  • Ballatori N, Christian WV, Lee JY, et al. (2005). "OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia.". Hepatology 42 (6): 1270–9. doi:10.1002/hep.20961. PMID 16317684. 
  • Boyer JL, Trauner M, Mennone A, et al. (2006). "Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents.". Am. J. Physiol. Gastrointest. Liver Physiol. 290 (6): G1124–30. doi:10.1152/ajpgi.00539.2005. PMID 16423920. 
  • Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.". Cell 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. 
  • Sun AQ, Balasubramaniyan N, Xu K, et al. (2007). "Protein-protein interactions and membrane localization of the human organic solute transporter.". Am. J. Physiol. Gastrointest. Liver Physiol. 292 (6): G1586–93. doi:10.1152/ajpgi.00457.2006. PMID 17332473. 
 This article on a gene on chromosome 3 is a stub. You can help Wikipedia by expanding it.