OSBPL11

From Wikipedia, the free encyclopedia


Oxysterol binding protein-like 11
PDB rendering based on 2d9x.
Available structures: 2d9x
Identifiers
Symbol(s) OSBPL11; FLJ13012; FLJ13164; ORP-11; ORP11; OSBP12; TCCCIA00292
External IDs OMIM: 606739 MGI2146553 HomoloGene23385
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 114885 106326
Ensembl ENSG00000144909 ENSMUSG00000022807
Uniprot Q9BXB4 Q8CI95
Refseq NM_022776 (mRNA)
NP_073613 (protein)
NM_176840 (mRNA)
NP_789810 (protein)
Location Chr 3: 126.73 - 126.8 Mb Chr 16: 33.1 - 33.16 Mb
Pubmed search [1] [2]

Oxysterol binding protein-like 11, also known as OSBPL11, is a human gene.[1]

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain.[1]

[edit] References

[edit] Further reading

  • Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474. 
  • Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353–8. PMID 9110174. 
  • Lehto M, Laitinen S, Chinetti G, et al. (2001). "The OSBP-related protein family in humans.". J. Lipid Res. 42 (8): 1203–13. PMID 11483621. 
  • Jaworski CJ, Moreira E, Li A, et al. (2002). "A family of 12 human genes containing oxysterol-binding domains.". Genomics 78 (3): 185–96. doi:10.1006/geno.2001.6663. PMID 11735225. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. 
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.