Talk:Orthomolecular medicine/1 paragraph lede/

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[edit] OMM current version

Orthomolecular medicine is a form of complementary and alternative medicine that aims to treat disease by restoring the optimum environment of the body by correcting what proponents argue to be the metabolic imbalances or deficiencies causing disease.[1][2] It is based on individual biochemistry, using naturally-occurring or bioequivalent (bio)molecules, such as vitamins, dietary minerals, proteins, antioxidants, amino acids, lipotropes, prohormones, dietary fiber and fatty acids. It holds that such imbalances or deficiencies can be prevented and treated by achieving optimum bodily levels of these substances.[3]

The term "orthomolecular medicine" was first described by Linus Pauling in 1967, but concepts frequently utilized in orthomolecular medicine, including individual biochemical variation, inborn error of metabolism, and exogeneous supply of essential substances in therapy date back to the early 20th century. Some conventional therapies use nutrients, such as using niacin to treat dyslipidemia,[4] and some research investigating therapeutic uses of nutrients has been published in mainstream sources.[5][6][7] However, the scientific and medical consensus is that the broad claims of efficacy advanced by advocates of orthomolecular medicine are unsupported,[8][9] with the American Medical Association saying that the idea that most diseases can be prevented by nutritional interventions is a myth.[10]

refs = 1 - 10 (where 1 = 11, 13, 14 duplicates below)

[edit] Orthomolecular medicine - lead paragraph proposals

[edit] 1. "version 0.90"

Orthomolecular medicine is a form of alternative medicine,[11] which aims to restore the optimum environment of the body by correcting imbalances or deficiencies based on individual biochemistry using substances natural to the body such as vitamins, dietary minerals, proteins, antioxidants, amino acids, ω-3 fatty acids, ω-6 fatty acids, lipotropes, prohormones, dietary fiber and short and long chain fatty acids. It holds that such imbalances or deficiencies can be prevented, treated, or sometimes cured by achieving optimum bodily levels of these substances, either through diet or metabolism.[3] While many medical experts conclude that the claims of orthmolecular medicine are unsubstantiated,[12] research validating concepts associated with orthomolecular medicine has gained recognition in mainstream sources.[5] [6] [7]

refs = 3, 5, 6, 7 , 11, 12

[edit] 2. a slight update

Orthomolecular medicine is a form of complementary and alternative medicine,[13] which aims to restore the optimum environment of the body by correcting imbalances or deficiencies based on individual biochemistry using substances natural to the body such as vitamins, dietary minerals, proteins, antioxidants, amino acids, ω-3 fatty acids, ω-6 fatty acids, lipotropes, prohormones, dietary fiber and short and long chain fatty acids. It holds that such imbalances or deficiencies can be prevented, treated, or sometimes cured by achieving optimum bodily levels of these substances, either through diet or metabolism.[3] While many medical experts conclude that the claims of orthmolecular medicine are unsubstantiated,[12] research validating concepts associated with orthomolecular medicine has gained recognition in mainstream sources.[5] [6] [7]--TheNautilus (talk) 00:32, 22 March 2008 (UTC)

refs = 3, 5, 6, 7, 12, 13

[edit] 3. toward a knowledgeable, NPOV, short, comprehensive summary

Orthomolecular medicine is a form of complementary and alternative medicine that aims to restore the optimum environment of the body by correcting proposed metabolic imbalances or deficiencies associated with disease.[14][15] It is based on individual biochemistry, using naturally-occurring or bioequivalent (bio)molecules, such as vitamins, dietary minerals, proteins, antioxidants, amino acids, lipotropes, prohormones, dietary fiber and fatty acids. Orthomolecular medicine holds that such imbalances, deficiencies or many diseases can be prevented and treated by achieving optimum bodily levels of these substances.[3]

Popularly based since Linus Pauling defined and publicly advocated orthomolecular medicine starting in the 1960s, along with Abram Hoffer, it is founded on early research, preliminary clinical studies and observations throughout the 20th century.{{cn)} A controversial field deprecated by some critics,[12] such as the ACSref1 and parts of the AMA.ref2 Many medical commentators conclude that the medical claims of orthmolecular medicine and nutrition are unsubstantiated or inadequately proven by modern pharmaceutical style tests and need more scientific research to support its claims.[16] Some recent research validating concepts associated with orthomolecular medicine has gained recognition in mainstream sources.[5][6][7]--TheNautilus (talk) 00:32, 22 March 2008 (UTC)

refs = (1=14), (2=15), 3, 5, 6, 7, 12, 14, 15, 16 (8, 9, 10 appear short, weak blurbs, 4 gone with too much pro(?) OMM detail)

  1. ^ Orthomolecular medicine Encyclopedia of Alternative Medicine by Patricia Skinner
  2. ^ Complementary and Alternative Medicine (CAM): Types of Complementary and Alternative Medicine Section on Complementary and Alternative Medicine (CAM) in the The Merck Manual Online, 18th Edition, Accessed 20 March 08
  3. ^ a b c d Definition of Orthomolecular medicine at www.orthomed.org Accessed June 2006
  4. ^ Guyton JR (2007). "Niacin in cardiovascular prevention: mechanisms, efficacy, and safety". Curr. Opin. Lipidol. 18 (4): 415-20. doi:10.1097/MOL.0b013e3282364add. PMID 17620858. 
  5. ^ a b c d Eat it up and be a good boy. The Economist, February 2, 2008
  6. ^ a b c d Gesch CB et al, Influence of supplementary vitamins, minerals and essential fatty acids on the antisocial behaviour of young adult prisoners. Randomised, placebo-controlled trial., Br J Psych, 2002, Vol. 181, pp. 22-28 2002
  7. ^ a b c d Research backs theory that vitamin C shrinks tumours. The Independent, 28 March 2006
  8. ^ Jarvis WT (1983). "Food faddism, cultism, and quackery". Annu. Rev. Nutr. 3: 35-52. doi:10.1146/annurev.nu.03.070183.000343. PMID 6315036. 
  9. ^ Stuart Aaronson et. al. "Cancer Medicine", 2003, BC Decker Inc ISBN 1–55009–213–8, Section 20, p76
  10. ^ Report 12 of the Council on Scientific Affairs: Alternative medicine American Medical Association June 1997, Accessed 21 March 2008
  11. ^ Orthomolecular medicine Encyclopedia of Alternative Medicine by Patricia Skinner
  12. ^ a b c Barrett, Stephen (2000-07-12). Orthomolecular Therapy. Retrieved on 2008-02-08.
  13. ^ Orthomolecular medicine Encyclopedia of Alternative Medicine by Patricia Skinner
  14. ^ Orthomolecular medicine Encyclopedia of Alternative Medicine by Patricia Skinner
  15. ^ Complementary and Alternative Medicine (CAM): Types of Complementary and Alternative Medicine Section on Complementary and Alternative Medicine (CAM) in the The Merck Manual Online, 18th Edition, Accessed 20 March 08
  16. ^ Menolascino FJ, et al. "Orthomolecular Therapy: Its History and Applicability to Psychiatric Disorders", Child Psychiatry and Human Development, Vol.18(3), Spring 1988, pp 140-1

[edit] Comments

[edit] partisan text

moved partisan text for editing (discussion on main Talk page?) Orthomolecular medicine has even been described as a form of food faddism and quackery. I believe that this is something that needs to be worked out in the body first, too--TheNautilus (talk) 19:06, 2 April 2008 (UTC)