OR9A4

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Olfactory receptor, family 9, subfamily A, member 4
Identifiers
Symbol(s) OR9A4;
External IDs MGI3030294 HomoloGene64866
Orthologs
Human Mouse
Entrez 130075 258381
Ensembl n/a ENSMUSG00000045514
Refseq NM_001001656 (mRNA)
NP_001001656 (protein)
NM_146383 (mRNA)
NP_666495 (protein)
Location n/a Chr 6: 40.5 - 40.5 Mb
Pubmed search [1] [2]

Olfactory receptor, family 9, subfamily A, member 4, also known as OR9A4, is a human gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

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[edit] Further reading

  • Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767–72. doi:10.1126/science.1083423. PMID 12690205. 
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. PMID 14983052. 

[edit] External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.