OR8B8
From Wikipedia, the free encyclopedia
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Olfactory receptor, family 8, subfamily B, member 8
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| Identifiers | ||||||||||||||
| Symbol(s) | OR8B8; TPCR85 | |||||||||||||
| External IDs | MGI: 2177528 HomoloGene: 56568 | |||||||||||||
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| RNA expression pattern | ||||||||||||||
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| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 26493 | 258310 | ||||||||||||
| Ensembl | ENSG00000197125 | ENSMUSG00000066748 | ||||||||||||
| Uniprot | Q15620 | Q60882 | ||||||||||||
| Refseq | NM_012378 (mRNA) NP_036510 (protein) |
NM_146313 (mRNA) NP_666425 (protein) |
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| Location | Chr 11: 123.82 - 123.82 Mb | Chr 9: 37.65 - 37.65 Mb | ||||||||||||
| Pubmed search | [1] | [2] | ||||||||||||
Olfactory receptor, family 8, subfamily B, member 8, also known as OR8B8, is a human gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
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[edit] See also
[edit] References
[edit] Further reading
- Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (1997). "Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.". Genomics 39 (3): 239-46. doi:. PMID 9119360.
- Gaudin JC, Breuils L, Haertlé T (2002). "New GPCRs from a human lingual cDNA library.". Chem. Senses 26 (9): 1157-66. PMID 11705801.
- Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295-302. PMID 12213199.
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052.
[edit] External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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