OR7C2
From Wikipedia, the free encyclopedia
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Olfactory receptor, family 7, subfamily C, member 2
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| Identifiers | ||||||||||||||
| Symbol(s) | OR7C2; CIT-HSP-87M17; OR19-18; OR7C3 | |||||||||||||
| External IDs | MGI: 3031190 HomoloGene: 71958 | |||||||||||||
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| RNA expression pattern | ||||||||||||||
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| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 26658 | 258305 | ||||||||||||
| Ensembl | ENSG00000127529 | ENSMUSG00000051190 | ||||||||||||
| Uniprot | O60412 | n/a | ||||||||||||
| Refseq | NM_012377 (mRNA) NP_036509 (protein) |
NM_146308 (mRNA) NP_666420 (protein) |
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| Location | Chr 19: 14.91 - 14.91 Mb | Chr 10: 78.25 - 78.25 Mb | ||||||||||||
| Pubmed search | [1] | [2] | ||||||||||||
Olfactory receptor, family 7, subfamily C, member 2, also known as OR7C2, is a human gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
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[edit] See also
[edit] References
[edit] Further reading
- Rouquier S, Taviaux S, Trask BJ, et al. (1998). "Distribution of olfactory receptor genes in the human genome.". Nat. Genet. 18 (3): 243-50. doi:. PMID 9500546.
- Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295-302. PMID 12213199.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:. PMID 12477932.
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052.
- Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19.". Nature 428 (6982): 529-35. doi:. PMID 15057824.
[edit] External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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