OR7C1

From Wikipedia, the free encyclopedia


Olfactory receptor, family 7, subfamily C, member 1
Identifiers
Symbol(s) OR7C1; CIT-HSP-146E8; HSTPCR86P; OR19-5; OR7C4; TPCR86
External IDs MGI3030704 HomoloGene27294
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 26664 57251
Ensembl ENSG00000127530 ENSMUSG00000066899
Uniprot O76099 n/a
Refseq NM_198944 (mRNA)
NP_945182 (protein)
NM_146904 (mRNA)
NP_667115 (protein)
Location Chr 19: 14.77 - 14.77 Mb Chr 9: 19.92 - 19.92 Mb
Pubmed search [1] [2]

Olfactory receptor, family 7, subfamily C, member 1, also known as OR7C1, is a human gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

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[edit] References

[edit] Further reading

  • Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (1997). "Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.". Genomics 39 (3): 239-46. doi:10.1006/geno.1996.4490. PMID 9119360. 
  • Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (1997). "Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome.". Biochem. Biophys. Res. Commun. 237 (2): 283-7. doi:10.1006/bbrc.1997.7043. PMID 9268701. 
  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295-302. PMID 12213199. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052. 

[edit] External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.