OR6C3

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Olfactory receptor, family 6, subfamily C, member 3
Identifiers
Symbol(s) OR6C3; OST709
External IDs MGI3030622 HomoloGene74200
Orthologs
Human Mouse
Entrez 254786 258544
Ensembl ENSG00000205329 ENSMUSG00000049217
Uniprot Q9NZP0 n/a
Refseq NM_054104 (mRNA)
NP_473445 (protein)
NM_146551 (mRNA)
NP_666762 (protein)
Location Chr 12: 54.01 - 54.01 Mb Chr 10: 128.88 - 128.88 Mb
Pubmed search [1] [2]

Olfactory receptor, family 6, subfamily C, member 3, also known as OR6C3, is a human gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

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[edit] Further reading

  • Rouquier S, Blancher A, Giorgi D (2000). "The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates.". Proc. Natl. Acad. Sci. U.S.A. 97 (6): 2870–4. doi:10.1073/pnas.040580197. PMID 10706615. 
  • Scherer SE, Muzny DM, Buhay CJ, et al. (2006). "The finished DNA sequence of human chromosome 12.". Nature 440 (7082): 346–51. doi:10.1038/nature04569. PMID 16541075. 

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.