OR6C2
From Wikipedia, the free encyclopedia
Olfactory receptor, family 6, subfamily C, member 2
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Identifiers | ||||||||||||||
Symbol(s) | OR6C2; OR6C67 | |||||||||||||
External IDs | MGI: 3030625 HomoloGene: 45066 | |||||||||||||
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Orthologs | ||||||||||||||
Human | Mouse | |||||||||||||
Entrez | 341416 | 258932 | ||||||||||||
Ensembl | ENSG00000179695 | ENSMUSG00000047626 | ||||||||||||
Uniprot | Q9NZP2 | n/a | ||||||||||||
Refseq | NM_054105 (mRNA) NP_473446 (protein) |
NM_146930 (mRNA) NP_667141 (protein) |
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Location | Chr 12: 54.13 - 54.13 Mb | Chr 10: 128.93 - 128.93 Mb | ||||||||||||
Pubmed search | [1] | [2] |
Olfactory receptor, family 6, subfamily C, member 2, also known as OR6C2, is a human gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
[edit] See also
[edit] References
[edit] Further reading
- Rouquier S, Blancher A, Giorgi D (2000). "The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates.". Proc. Natl. Acad. Sci. U.S.A. 97 (6): 2870–4. doi: . PMID 10706615.
- Scherer SE, Muzny DM, Buhay CJ, et al. (2006). "The finished DNA sequence of human chromosome 12.". Nature 440 (7082): 346–51. doi: . PMID 16541075.
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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