OR5D18

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Olfactory receptor, family 5, subfamily D, member 18
Identifiers
Symbol(s) OR5D18; OR11-143
External IDs MGI2151908 HomoloGene50502
Orthologs
Human Mouse
Entrez 219438 117004
Ensembl ENSG00000186119 ENSMUSG00000075140
Uniprot Q8NGL1 n/a
Refseq NM_001001952 (mRNA)
NP_001001952 (protein)
NM_054090 (mRNA)
NP_473431 (protein)
Location Chr 11: 55.34 - 55.34 Mb Chr 2: 87.84 - 87.84 Mb
Pubmed search [1] [2]

Olfactory receptor, family 5, subfamily D, member 18, also known as OR5D18, is a human gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

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[edit] Further reading

  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295–302. PMID 12213199. 
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. PMID 14983052. 

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.