OR5B2

From Wikipedia, the free encyclopedia


Olfactory receptor, family 5, subfamily B, member 2
Identifiers
Symbol(s) OR5B2; OR11-240; OST073
External IDs MGI3031285 HomoloGene85932
Orthologs
Human Mouse
Entrez 390190 258700
Ensembl ENSG00000172365 ENSMUSG00000046913
Uniprot Q96R09 n/a
Refseq NM_001005566 (mRNA)
NP_001005566 (protein)
NM_146705 (mRNA)
NP_666916 (protein)
Location Chr 11: 57.95 - 57.95 Mb Chr 19: 13.07 - 13.07 Mb
Pubmed search [1] [2]

Olfactory receptor, family 5, subfamily B, member 2, also known as OR5B2, is a human gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

Contents

[edit] See also

[edit] References

[edit] Further reading

  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295–302. PMID 12213199. 
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. PMID 14983052. 

[edit] External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.