OR5B12

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Olfactory receptor, family 5, subfamily B, member 12
Identifiers
Symbol(s) OR5B12; OR11-241; OR5B12P; OR5B16; OST743
External IDs MGI3031282 HomoloGene64905
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 390191 258696
Ensembl ENSG00000172362 ENSMUSG00000048456
Uniprot Q96R08 n/a
Refseq NM_001004733 (mRNA)
NP_001004733 (protein)
NM_146701 (mRNA)
NP_666912 (protein)
Location Chr 11: 57.96 - 57.96 Mb Chr 19: 12.99 - 12.99 Mb
Pubmed search [1] [2]

Olfactory receptor, family 5, subfamily B, member 12, also known as OR5B12, is a human gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

Contents

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[edit] References

[edit] Further reading

  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes.". Genomics 80 (3): 295–302. PMID 12213199. 
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. PMID 14983052. 

[edit] External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.