OR52D1
From Wikipedia, the free encyclopedia
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Olfactory receptor, family 52, subfamily D, member 1
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| Identifiers | ||||||||||||||
| Symbol(s) | OR52D1; OR11-43 | |||||||||||||
| External IDs | MGI: 3030480 HomoloGene: 17481 | |||||||||||||
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| RNA expression pattern | ||||||||||||||
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| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 390066 | 259058 | ||||||||||||
| Ensembl | ENSG00000181609 | ENSMUSG00000073931 | ||||||||||||
| Uniprot | Q9H346 | n/a | ||||||||||||
| Refseq | NM_001005163 (mRNA) NP_001005163 (protein) |
NM_147056 (mRNA) NP_667267 (protein) |
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| Location | Chr 11: 5.47 - 5.47 Mb | Chr 7: 103.98 - 103.98 Mb | ||||||||||||
| Pubmed search | [1] | [2] | ||||||||||||
Olfactory receptor, family 52, subfamily D, member 1, also known as OR52D1, is a human gene.[1]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
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[edit] See also
[edit] References
[edit] Further reading
- Bulger M, van Doorninck JH, Saitoh N, et al. (1999). "Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes.". Proc. Natl. Acad. Sci. U.S.A. 96 (9): 5129–34. PMID 10220430.
- Bulger M, Bender MA, van Doorninck JH, et al. (2001). "Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.". Proc. Natl. Acad. Sci. U.S.A. 97 (26): 14560–5. doi:. PMID 11121057.
- Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. PMID 14983052.
[edit] External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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