OR52A5

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Olfactory receptor, family 52, subfamily A, member 5
Identifiers
Symbol(s) OR52A5; OR11-33
External IDs MGI1341790 HomoloGene8420
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 390054 18369
Ensembl ENSG00000171944 ENSMUSG00000061626
Uniprot Q9H2C5 n/a
Refseq NM_001005160 (mRNA)
NP_001005160 (protein)
NM_013620 (mRNA)
NP_038648 (protein)
Location Chr 11: 5.11 - 5.11 Mb Chr 7: 103.65 - 103.65 Mb
Pubmed search [1] [2]

Olfactory receptor, family 52, subfamily A, member 5, also known as OR52A5, is a human gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

Contents

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[edit] References

[edit] Further reading

  • Bulger M, Bender MA, van Doorninck JH, et al. (2001). "Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.". Proc. Natl. Acad. Sci. U.S.A. 97 (26): 14560-5. doi:10.1073/pnas.97.26.14560. PMID 11121057. 
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052. 

[edit] External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.