OR4L1

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Olfactory receptor, family 4, subfamily L, member 1
Identifiers
Symbol(s) OR4L1; OR14-28; OR4L2P
External IDs MGI3030558 HomoloGene71986
Orthologs
Human Mouse
Entrez 122742 258485
Ensembl ENSG00000176246 ENSMUSG00000058227
Uniprot Q8NH43 n/a
Refseq XM_939518 (mRNA)
XP_944611 (protein)
NM_146492 (mRNA)
NP_666703 (protein)
Location Chr 14: 19.6 - 19.6 Mb Chr 14: 48.88 - 48.88 Mb
Pubmed search [1] [2]

Olfactory receptor, family 4, subfamily L, member 1, also known as OR4L1, is a human gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

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[edit] Further reading

  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584-9. PMID 14983052. 

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.